Insulin is a polypeptide hormone mainly secreted by β cells in the islets of Langerhans of the
pancreas. The hormone potentially coordinates with glucagon to modulate blood glucose …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

Is the field of cognitive aging irretrievably concerned with decline and deficits, or is it shifting
to emphasize the hope of preservation and enhancement of cognitive function in late life? A …

While the central nervous system compromises 2% of our body weight, it harbors up to 25%
of the body's cholesterol. Cholesterol levels in the brain are tightly regulated for …

Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

The relationship between obesity and cognitive impairment is important given the globally
ageing population in whom cognitive decline and neurodegenerative disorders will carry …

Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Cognitive function is an important component of aging and predicts quality of life, functional
independence, and risk of institutionalization. Advances in our understanding of the role of …

A growing body of evidence suggests that adherence to the Mediterranean diet (MD) may
protect against cognitive decline and dementia. Many epidemiologic studies and several …

Introduction We examined whether obesity at ages 50, 60, and 70 years is associated with
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …