Epigallocatechin 3-gallate: From green tea to cancer therapeutics
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …
D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Green tea catechins: nature's way of preventing and treating cancer
M Farhan - International journal of molecular sciences, 2022 - mdpi.com
Green tea's (Camellia sinensis) anticancer and anti-inflammatory effects are well-known.
Catechins are the most effective antioxidants among the physiologically active compounds …
Catechins are the most effective antioxidants among the physiologically active compounds …
[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy
W Liu, X Cui, Y Zhong, R Ma, B Liu, Y Xia - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …
Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2
A Du, R Zheng, C Disoma, S Li, Z Chen, S Li… - International journal of …, 2021 - Elsevier
SARS-CoV-2 is the etiological agent responsible for the ongoing pandemic of coronavirus
disease 2019 (COVID-19). The main protease of SARS-CoV-2, 3CLpro, is an attractive …
disease 2019 (COVID-19). The main protease of SARS-CoV-2, 3CLpro, is an attractive …
The potential of epigallocatechin gallate (EGCG) in targeting autophagy for cancer treatment: A narrative review
E Ferrari, S Bettuzzi, V Naponelli - International journal of molecular …, 2022 - mdpi.com
Autophagy is an evolutionarily conserved process for the degradation of redundant or
damaged cellular material by means of a lysosome-dependent mechanism, contributing to …
damaged cellular material by means of a lysosome-dependent mechanism, contributing to …
The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy
M Garg, MK Shanmugam, V Bhardwaj… - Medicinal research …, 2021 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
DYRK1A inhibitors for disease therapy: Current status and perspectives
Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a conserved
protein kinase that plays essential roles in various biological processes. It is located in the …
protein kinase that plays essential roles in various biological processes. It is located in the …
Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …
is involved in several cancer developments, including NSCLC. The EGFR pathway …
Recent updates on anticancer mechanisms of polyphenols
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …
compounds become imperative. Studies on the molecular mechanisms of action of …