Intermittent fasting and the possible benefits in obesity, diabetes, and multiple sclerosis: a systematic review of randomized clinical trials

M Morales-Suarez-Varela, E Collado Sanchez… - Nutrients, 2021 - mdpi.com
Intermittent fasting has become popular in recent years and is controversially presented as a
possible therapeutic adjunct. A bibliographic review of the literature on intermittent fasting …

Seven decades of Ramadan intermittent fasting research: Bibliometrics analysis, global trends, and future directions

K Obaideen, KHA Shihab, MI Madkour… - Diabetes & Metabolic …, 2022 - Elsevier
Background and aims There is a large body of research focused on various aspects related
to Ramadan intermittent fasting (RIF) and human health and disease. This study aimed to …

[HTML][HTML] Leveraging 3D printing to enhance mass spectrometry: A review

M Grajewski, M Hermann, RD Oleschuk… - Analytica Chimica …, 2021 - Elsevier
The use of 3D printing in the chemical and analytical sciences has gained a lot of
momentum in recent years. Some of the earliest publications detailed 3D-printed interfaces …

[HTML][HTML] Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of …

AL Mindikoglu, MM Abdulsada, A Jain, JM Choi… - Journal of …, 2020 - Elsevier
Murine studies showed that disruption of circadian clock rhythmicity could lead to cancer
and metabolic syndrome. Time-restricted feeding can reset the disrupted clock rhythm …

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

AL Kearney, DM Norris, M Ghomlaghi, M Kin Lok Wong… - Elife, 2021 - elifesciences.org
The phosphoinositide 3-kinase (PI3K)-Akt network is tightly controlled by feedback
mechanisms that regulate signal flow and ensure signal fidelity. A rapid overshoot in insulin …

The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus

JY Lee, DJ Harney, JD Teo, JB Kwok… - Molecular …, 2023 - Springer
Background The risk for dementia increases exponentially from the seventh decade of life.
Identifying and understanding the biochemical changes that sensitize the ageing brain to …

[PDF][PDF] Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

ID Green, N Pinello, R Song, Q Lee… - Nucleic Acids …, 2020 - academic.oup.com
Monocytes and macrophages are essential components of the innate immune system.
Herein, we report that intron retention (IR) plays an important role in the development and …

Proteomics analysis of adipose depots after intermittent fasting reveals visceral fat preservation mechanisms

DJ Harney, M Cielesh, R Chu, KC Cooke, DE James… - Cell reports, 2021 - cell.com
Intermittent fasting is a beneficial dietary treatment for obesity. But the response of each
distinct adipose depot is currently poorly defined. Here we explore the response of key …

Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsia

H Chen, I Aneman, V Nikolic, N Karadzov Orlic… - Scientific reports, 2022 - nature.com
Preeclampsia is still the leading cause of morbidity and mortality in pregnancy without a
cure. There are two phenotypes of preeclampsia, early-onset (EOPE) and late-onset (LOPE) …

A multiomics dataset for the study of RNA modifications in human macrophage differentiation and polarisation

N Pinello, R Song, Q Lee, E Calonne, M Larance… - Scientific Data, 2024 - nature.com
RNA modifications have emerged as central regulators of gene expression programs.
Amongst RNA modifications are N6-methyladenosine (m6A) and RNA 5 …