[HTML][HTML] A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory …

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
The impacts of air pollution on public health have become a great concern worldwide.
Ambient particulate matter (PM) is a major air pollution that comprises a heterogeneous …

Overview of PM2. 5 and health outcomes: focusing on components, sources, and pollutant mixture co-exposure

N Nan, Z Yan, Y Zhang, R Chen, G Qin, N Sang - Chemosphere, 2023 - Elsevier
PM 2.5 varies in source and composition over time and space as a complicated mixture.
Consequently, the health effects caused by PM 2.5 varies significantly over time and …

AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2. 5 in zebrafish embryos

F Ren, C Ji, Y Huang, S Aniagu, Y Jiang… - Science of the Total …, 2020 - Elsevier
Recent studies have shown an association between maternal exposure to ambient fine
particle matter (PM2. 5) and congenital heart defects in the offspring, but the underlying …

Hexavalent chromium induced heart dysfunction via Sesn2-mediated impairment of mitochondrial function and energy supply

D Yang, Q Yang, N Fu, S Li, B Han, Y Liu, Y Tang… - Chemosphere, 2021 - Elsevier
Abstract Hexavalent chromium (Cr (VI)), the most toxic valence state of chromium, is widely
present in industrial effluents and wastes. Although previous study has reported that Cr (VI) …

[HTML][HTML] The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer

L Zhang, Y Li, Q Wang, Z Chen, X Li, Z Wu, C Hu… - Molecular Cancer, 2020 - Springer
Abstract Background PI3K/AKT is a vital signaling pathway in humans. Recently, several
PI3K/AKT inhibitors were reported to have the ability to reverse cancer multidrug resistance …

[HTML][HTML] The pathophysiological and molecular mechanisms of atmospheric PM2. 5 affecting cardiovascular health: A review

S Feng, F Huang, Y Zhang, Y Feng, Y Zhang… - Ecotoxicology and …, 2023 - Elsevier
Background Exposure to ambient fine particulate matter (PM 2.5, with aerodynamic diameter
less than 2.5 µm) is a leading environmental risk factor for global cardiovascular health …

[HTML][HTML] The impact of particulate matters on apoptosis in various organs: mechanistic and therapeutic perspectives

SM Aghaei-Zarch, AHS Nia, M Nouri… - Biomedicine & …, 2023 - Elsevier
Ecological air contamination is the non-homogenous suspension of insoluble particles into
gas or/and liquid fluids known as particulate matter (PM). It has been discovered that …

Adverse outcome pathway of fine particulate matter leading to increased cardiovascular morbidity and mortality: an integrated perspective from toxicology and …

Y Yu, Q Sun, T Li, X Ren, L Lin, M Sun, J Duan… - Journal of hazardous …, 2022 - Elsevier
Abstract Fine particulate matter (PM 2.5) exposure is a major threat to public health, and is
listed as one of the leading factors associated with global premature mortality. Among the …

Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2. 5 induced cardiac fibrosis

H Hu, L Li, H Zhang, Y Zhang, Q Liu, M Chen, J Ning… - Chemosphere, 2023 - Elsevier
Epidemiological studies have demonstrated strong associations between exposure to
ambient fine particulate matter (PM2. 5) and cardiac disease. To investigate the potential …

[HTML][HTML] PM2. 5-related cell death patterns

Y Wang, Y Zhong, J Liao, G Wang - International Journal of …, 2021 - ncbi.nlm.nih.gov
With the increasingly serious problem of environmental pollution, the health problems
caused by PM2. 5 are gradually coming into our line of sight. Previous researches have …