[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
Epigenetic alterations in the gastrointestinal tract: current and emerging use for biomarkers of cancer
WM Grady - Advances in cancer research, 2021 - Elsevier
Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
Epigenetic alterations in colorectal cancer: emerging biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …
fundamental processes driving the initiation and progression of CRC is the accumulation of …
[HTML][HTML] Colorectal cancer: from prevention to personalized medicine
G Binefa, F Rodríguez-Moranta, À Teule… - World journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a very heterogeneous disease that is caused by the interaction
of genetic and environmental factors. CRC develops through a gradual accumulation of …
of genetic and environmental factors. CRC develops through a gradual accumulation of …
DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
Surveillance after curative treatment for colorectal cancer
EP van der Stok, MCW Spaander… - Nature reviews Clinical …, 2017 - nature.com
Treatments for colorectal cancer (CRC) of all stages have evolved considerably over the
past two decades, resulting in improved long-term outcomes. After curative treatment …
past two decades, resulting in improved long-term outcomes. After curative treatment …
Cell-free DNA in the blood as a solid tumor biomarker—a critical appraisal of the literature
K Jung, M Fleischhacker, A Rabien - Clinica chimica acta, 2010 - Elsevier
Circulating cell-free DNA (cfDNA) has been suggested as a cancer biomarker. Several
studies assessed the usefulness of quantitative and qualitative tumor-specific alterations of …
studies assessed the usefulness of quantitative and qualitative tumor-specific alterations of …
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay
R Grützmann, B Molnar, C Pilarsky, JK Habermann… - PloS one, 2008 - journals.plos.org
Background Colorectal cancer (CRC) is the second leading cause of cancer deaths despite
the fact that detection of this cancer in early stages results in over 90% survival rate …
the fact that detection of this cancer in early stages results in over 90% survival rate …
DNA methylation markers in colorectal cancer
MS Kim, J Lee, D Sidransky - Cancer and Metastasis Reviews, 2010 - Springer
Colorectal cancer (CRC) arises as a consequence of the accumulation of genetic and
epigenetic alterations in colonic epithelial cells during neoplastic transformation. Epigenetic …
epigenetic alterations in colonic epithelial cells during neoplastic transformation. Epigenetic …
Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer
JMK Ng, J Yu - International journal of molecular sciences, 2015 - mdpi.com
Colorectal cancer (CRC) is a common malignancy and the fourth leading cause of cancer
deaths worldwide. It results from the accumulation of multiple genetic and epigenetic …
deaths worldwide. It results from the accumulation of multiple genetic and epigenetic …