The roles of gut microbiota and its metabolites in diabetic nephropathy
H Zhao, CE Yang, T Liu, MX Zhang, Y Niu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which
increases the risk of renal failure and causes a high global disease burden. Due to the lack …
increases the risk of renal failure and causes a high global disease burden. Due to the lack …
Molecular mechanisms of diabetic nephropathy: A narrative review
T Sun, Y Guo, Y Su, S Shan, W Qian… - Cell Biology …, 2024 - Wiley Online Library
Diabetic nephropathy (DN) is the predominant secondary nephropathy resulting in global
end‐stage renal disease. It is attracting significant attention in both domestic and …
end‐stage renal disease. It is attracting significant attention in both domestic and …
Expression of pro-inflammatory cytokines (IL-6 & IL-18) exacerbate the risk of diabetic nephropathy in the Pakistani population
M Maqsood, S Sharif, S Naz, T Farasat… - Molecular Biology …, 2023 - Springer
Background Diabetic nephropathy (DN) is a micro-chronic diabetic consequence induced by
metabolic and hemodynamic abnormalities. Free radicals react with other critical cellular …
metabolic and hemodynamic abnormalities. Free radicals react with other critical cellular …
Renoprotective effect of a novel combination of 6-gingerol and metformin in high-fat diet/streptozotocin-induced diabetic nephropathy in rats via targeting miRNA-146a …
MG Aboismaiel, MN Amin, LA Eissa - Biological Research, 2024 - Springer
Background MiRNA-146a and miRNA-223 are key epigenetic regulators of toll-like receptor
4 (TLR4)/tumor necrosis factor-receptor-associated factor 6 (TRAF6)/NOD-like receptor …
4 (TLR4)/tumor necrosis factor-receptor-associated factor 6 (TRAF6)/NOD-like receptor …
Imperatorin ameliorates kidney injury in diabetic mice by regulating the TGF-β/Smad2/3 signaling axis, epithelial-to-mesenchymal transition, and renal inflammation
Diabetic nephropathy (DN) is a serious concern in patients with diabetes mellitus. Prolonged
hyperglycemia induces oxidative damage, chronic inflammation, and build-up of …
hyperglycemia induces oxidative damage, chronic inflammation, and build-up of …
Apolipoprotein E Gene Variation in Pakistani Subjects with Type 2 Diabetes with and without Cardiovascular Complications
S Nadeem, T Maqbool, JA Qureshi, A Altaf, S Naz… - Medicina, 2024 - mdpi.com
Background: Apolipoprotein E (APOE) gene polymorphism has been implicated in the
pathogenesis of various metabolic disorders, including type 2 diabetes mellitus (T2DM) …
pathogenesis of various metabolic disorders, including type 2 diabetes mellitus (T2DM) …
[HTML][HTML] The association between interleukin family and diabetes mellitus and its complications: An overview of systematic reviews and meta-analyses
Z Jin, Q Zhang, K Liu, S Wang, Y Yan, B Zhang… - Diabetes Research and …, 2024 - Elsevier
Objective To evaluate and summarize the association between interleukin (IL)
concentrations and diabetes mellitus (DM) and its complications. Methods Meta-analyses …
concentrations and diabetes mellitus (DM) and its complications. Methods Meta-analyses …
[HTML][HTML] Network pharmacology and molecular dynamics study of the effect of the Astragalus-Coptis drug pair on diabetic kidney disease
MY Zhang, SQ Zheng - World Journal of Diabetes, 2024 - ncbi.nlm.nih.gov
BACKGROUND Diabetic kidney disease (DKD) is the primary cause of end-stage renal
disease. The Astragalus-Coptis drug pair is frequently employed in the management of …
disease. The Astragalus-Coptis drug pair is frequently employed in the management of …
Association of circulatory PCSK-9 with biomarkers of redox imbalance and inflammatory cascades in the prognosis of diabetes and associated complications: a pilot …
Abstracts Besides the profound role of proprotein convertase subtilisin/kexin type-9 (PCSK-
9) in LDL-C regulation, its association with other metabolic complications cannot be …
9) in LDL-C regulation, its association with other metabolic complications cannot be …
Protective Effect of Saikosaponin D against Streptozotocin-Induced Diabetic Nephropathy in Rats by Regulating the Oxidative Stress and Inflammatory Markers
Y Chen, G Zhang, R Liang, Y Shen, X Jiao - Indian Journal of …, 2024 - ijper.org
Background Diabetic Nephropathy (DN) is a common problem in diabetes and is
characterized by glomerular dysfunction, hyperfiltration, and ultimately kidney failure …
characterized by glomerular dysfunction, hyperfiltration, and ultimately kidney failure …