Heterocyclic derivatives have more interesting biological properties which hold a
remarkable place in pharmaceutical industries due to their unique physiochemical …

In this present study on understanding the taxol (PTX) binding interaction mechanism in both
the β-tubulin and bovine serum albumin (BSA) molecule, various optical spectroscopy and …

4-[(1 Z)-1-(2-carbamothioylhydrazinylidene) ethyl] phenyl acetate [Ace semi], 4-[(1 Z)-1-(2-
carbamothioylhydrazinylidene) ethyl] phenyl propanoate [Pro semi] from the family of …

Chalcone derivatives are an extremely valuable class of compounds, primarily due to the
keto-ethylenic group, CO–CHCH–, they contain. Moreover, the presence of a reactive α, β …

The present study focuses on the determination of the biologically significant N-
acetylneuraminic acid (NANA) drug binding interaction mechanism between bovine serum …

The present studies used biophysical techniques to examine the binding interaction
mechanism of cytarabine anticancer drugs with human serum albumin (HSA) and …

Viral infections cause significant health problems all over the world, and it is critical to
develop treatments for these problems. Antivirals that target viral genome-encoded proteins …

4-[3-acetyl-5-(acetylamino)-2, 3-dihydro-1, 3, 4-thiadiazole-2-yl] phenyl benzoate from the
family of thiadiazole derivative has been newly synthesized. It has good anticancer activity …

In this study the interaction mechanism between newly synthesized 4‐(3‐acetyl‐5‐
(acetylamino)‐2‐methyl‐2, 3‐dihydro‐1, 3, 4‐thiadiazole‐2‐yl) phenyl benzoate (thiadiazole …

Fluorouracil (5-FU) is widely used for the cancer particularly for colorectal cancer. In
addition, it is accessible to the objective tissues in conjugation with transport protein serum …