Krüppel-like transcriptional factor is important in maintaining cellular functions. Deletion of
Krüppel-like transcriptional factor usually causes abnormal embryonic development and …

The interplay between microRNAs (miRNAs) and pluripotency transcription factors (TFs)
orchestrates the acquisition of cancer stem cell (CSC) features during the course of …

Background Acute kidney injury (AKI) is an emerging global healthcare issue without
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …

Abstract Introduction Pluripotent stem cells (PSCs) are promising tools for modern
regenerative medicine applications because of their stemness properties, which include …

Mounting evidence indicates that an increase in histone deacetylation contributes to renal
fibrosis. Although inhibition of histone deacetylase (HDAC) can reduce the extent of fibrosis …

Matrix metalloproteinase 9 (MMP-9) expression is upregulated in vascular inflammation and
participates in vascular remodeling, including aneurysm dilatation and arterial neointima …

Background Krüppel-like factors (KLFs) have been identified in multi-cancers and act as
oncogenes or tumor suppressors. The function of KLF15, one member of KLFs, has not been …

The transcription factor Krüppel-like factor 5 (KLF5) is highly expressed in many cancers and
serves as a prognostic factor. However, the function of KLF5 in hepatocellular carcinoma …

The reprogramming factor Krüppel-like factor 4 (Klf4), one of the Yamanaka's
reprogramming factors, plays an essential role in reprogramming somatic cells into induced …

Background Kruppel-like factor 4 (KLF4) is a zinc finger-containing transcription factor
predominantly expressed in terminally differentiated epithelial tissues. Many studies have …