Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Due to its poor prognosis and the late stage at which it is typically diagnosed, early detection
of pancreatic cancer is a pressing clinical problem. Advances in genomic analysis of human …

Pancreatic ductal adenocarcinoma is a lethal disease with limited treatment options and
poor survival. We studied 83 spatial samples from 31 patients (11 treatment-naïve and 20 …

Objectives: Previous retrospective studies demonstrated that circulating tumor cells (CTCs)
subtypes correlate with overall survival in patients with pancreatic ductal adenocarcinoma …

Early detection and diagnosis are the key to successful clinical management of pancreatic
cancer and improve the patient outcome. However, due to the absence of early symptoms …

Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …

Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second cause of
cancer-related deaths by 2020. Although it has traditionally been approached as a disease …

Pancreatic cancer is a highly aggressive malignancy with a climbing incidence. The majority
of cases are detected late, with incurable locally advanced or metastatic disease. Even in …

Circulating tumor cells (CTCs) are single cells or clusters of cells within the circulatory
system of a cancer patient. While most CTCs will perish, a small proportion will proceed to …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …