Myocardial infarction is defined as sudden ischemic death of myocardial tissue. In the
clinical context, myocardial infarction is usually due to thrombotic occlusion of a coronary …

Aging induces structural and functional changes in the heart that are associated with
increased risk of cardiovascular disease and impaired functional capacity in the elderly …

Tumour necrosis factor receptor-associated factor 6 (TRAF6) is a ubiquitin E3 ligase that
regulates important biological processes. However, the role of TRAF6 in cardiac hypertrophy …

Many anticancer strategies rely on the promotion of apoptosis in cancer cells as a means to
shrink tumors. Crucial for apoptotic function are executioner caspases, most notably …

Apoptosis, in contrast to other forms of cell death such as necrosis, was originally regarded
as a 'silent'mechanism of cell elimination designed to degrade the contents of doomed cells …

Muscle atrophy derived from excessive proteolysis is a hallmark of numerous disease
conditions. Accordingly, the negative consequences of skeletal muscle protein breakdown …

An innovative approach for cardiac regeneration following injury is to induce endogenous
cardiomyocyte (CM) cell cycle re-entry. In the present study, CMs from adult rat hearts were …

Abstract Ohwia caudata (Thunb.) H. Ohashi (Leguminosae) also called as “Evergreen
shrub” and Artemisia argyi H. Lév. and Vaniot (Compositae) also named as “Chinese …

Abstract Background Procaspase-3 (PC-3) is overexpressed in multiple tumour types and
procaspase-activating compound 1 (PAC-1) directly activates PC-3 and induces apoptosis …

The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal
MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key …