[HTML][HTML] Sulforaphane: A nutraceutical against diabetes-related complications

SXH Mthembu, SE Mazibuko-Mbeje… - Pharmacological …, 2023 - Elsevier
There is an increasing interest in the use of nutraceuticals and plant-derived bioactive
compounds from foods for their potential health benefits. For example, as a major active …

The improvement of sulforaphane in type 2 diabetes mellitus (T2DM) and related complications: a review

M Wang, M Chen, R Guo, Y Ding, H Zhang… - Trends in Food Science & …, 2022 - Elsevier
Background Type 2 diabetes mellitus (T2DM), one type of disease with severe disorders of
endocrine and metabolism, can induce lethal complications in various organs. Currently …

Sulforaphane promotes white matter plasticity and improves long-term neurological outcomes after ischemic stroke via the Nrf2 pathway

Q Li, G Fadoul, M Ikonomovic, T Yang… - Free Radical Biology and …, 2022 - Elsevier
Aims Post-stroke cognitive impairment (PSCI) is a common condition following ischemic
stroke. Neuronal loss and white matter injury are among the most common …

Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial …

FH Rizk, AA El Saadany, MM Atef… - … -European Journal of …, 2023 - Springer
Growing evidence supports the role of the gut-kidney axis and persistent mitochondrial
dysfunction in the pathogenesis of diabetic nephropathy (DN). Ulinastatin (UTI) has a potent …

Neuroprotective Effects of Sulforaphane in a Rat Model of Alzheimer's Disease Induced by Aβ (1-42) Peptides

WU Khan, M Salman, M Ali, H Majid, MS Yar… - Neurochemistry …, 2024 - Elsevier
The intricate nature of Alzheimer's disease (AD) has presented significant hurdles in the
development of effective interventions. Sulforaphane (SFN) is of interest due to its …

[HTML][HTML] Beneficial role of broccoli and its active ingredient, sulforaphane in the treatment of diabetes

A Mohammed, HA Mohammed - Phytomedicine Plus, 2023 - Elsevier
Background Broccoli and its active ingredient, sulforaphane were reported to possess
tremendous pharmacological activities such as anticancer, antimicrobial, antidepressant …

Neurobehavioral and neurobiochemical effect of atomoxetine and N-acetylcysteine in streptozotocin diabetes induced endothelial dysfunction and related dementia

H Aggarwal, S Gupta, P Sharma, BM Sharma… - Physiology & …, 2022 - Elsevier
Metabolic conditions like diabetes, is a major risk factor for the development of dementia of
vascular origin. This study investigates the efficacy of atomoxetine (ATX) and N …

Possible Prophylactic Effects of Sulforaphane on LPS-Induced Recognition Memory Impairment Mediated by Regulating Oxidative Stress and Neuroinflammatory …

NA Alzahrani, KA Bahaidrah, RA Mansouri… - Biomedicines, 2024 - mdpi.com
Background: Alzheimer's disease (AD) presents a significant global health concern,
characterized by neurodegeneration and cognitive decline. Neuroinflammation is a crucial …

Calcium Channels as a Potential Therapeutic Target for Alzheimer's Disease

P Sharma, P Thapak, B Chandwani, H Kharkwal… - … Drug Targets for …, 2023 - Springer
Alzheimer's disease (AD) is the most common type of dementia that characterizes the
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …

Montelukast Ameliorates 2K1C-Hypertension Induced Endothelial Dysfunction and Associated Vascular Dementia

S Gupta, P Singh, B Sharma - Current Hypertension Reviews, 2024 - ingentaconnect.com
Background: Declined kidney function associated with hypertension is a danger for cognitive
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …