Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109)

L Chen, XJ Shi, H Liu, X Mao, LN Gui, H Wang… - Translational …, 2021 - nature.com
There is increasing awareness that oxidative stress may be implicated in the
pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood …

Nutritional interventions for autism spectrum disorder

E Karhu, R Zukerman, RS Eshraghi, J Mittal… - Nutrition …, 2020 - academic.oup.com
Autism spectrum disorder (ASD) is an increasingly prevalent neurodevelopmental disorder
with considerable clinical heterogeneity. With no cure for the disorder, treatments commonly …

Modern biomarkers for autism spectrum disorder: future directions

AR Jensen, AL Lane, BA Werner, SE McLees… - Molecular Diagnosis & …, 2022 - Springer
Autism spectrum disorder is an increasingly prevalent neurodevelopmental disorder in the
world today, with an estimated 2% of the population being affected in the USA. A major …

Linking genetics to epigenetics: The role of folate and folate‐related pathways in neurodevelopmental disorders

C Lintas - Clinical genetics, 2019 - Wiley Online Library
There is growing evidence that epigenetic dysregulation plays a role in neurodevelopmental
disorders. In humans, folate is one of the main donors of the methyl group required for the …

[HTML][HTML] Association study of polymorphisms in genes relevant to vitamin B12 and folate metabolism with childhood autism spectrum disorder in a Han Chinese …

Z Zhang, L Yu, S Li, J Liu - Medical science monitor: international …, 2018 - ncbi.nlm.nih.gov
Background Both genetic and environmental factors play a role in the development of autism
spectrum disorder (ASD). This case-control study examined the association between …

Fisher discriminant analysis for classification of autism spectrum disorders based on folate-related metabolism markers

M Zou, C Sun, S Liang, Y Sun, D Li, L Li, L Fan… - The Journal of nutritional …, 2019 - Elsevier
Autism spectrum disorders (ASDs) are neurodevelopmental disorders with an increasing
prevalence but lack reliable biomarkers for early diagnosis. The present study investigated …

Sulfur amino acid metabolism and related metabotypes of autism spectrum disorder: A review of biochemical evidence for a hypothesis

NLR Indika, NEP Deutz, MPKJ Engelen, H Peiris… - Biochimie, 2021 - Elsevier
There are multiple lines of evidence for an impaired sulfur amino acid (SAA) metabolism in
autism spectrum disorder (ASD). For instance, the concentrations of methionine, cysteine …

Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics

SE John, D Antony, M Eaaswarkhanth, P Hebbar… - Scientific reports, 2018 - nature.com
Consanguineous populations of the Arabian Peninsula have been underrepresented in
global efforts that catalogue human exome variability. We sequenced 291 whole exomes of …

How matrix metalloproteinase (MMP)-9 (rs3918242) polymorphism affects MMP-9 serum concentration and associates with autism spectrum disorders: A case-control …

JR Lord, F Mashayekhi, Z Salehi - Development and …, 2022 - cambridge.org
The aim of this project was to evaluate the relationship of matrix metalloproteinase-9 (MMP-
9) genetic variation and its serum concentration with autism spectrum disorder (ASD). One …

Folate in maternal rheumatoid arthritis-filial autism spectrum disorder continuum

A Ravaei, M Rubini - Reproductive Toxicology, 2023 - Elsevier
Rheumatoid Arthritis (RA) is an inflammatory autoimmune disease that affects women three
times more than men. Epidemiological studies found that the incidence of Autism Spectrum …