Comprehensive guidance for antibiotic dosing in obese adults: 2022 update

L Meng, E Mui, DR Ha, C Stave… - … : The Journal of …, 2023 - Wiley Online Library
Drug dosing in obese patients continues to be challenging due to a lack of high‐quality
evidence to guide dosing recommendations. We first published guidance for antibiotic …

Updated antimicrobial dosing recommendations for obese patients

A Castro-Balado, I Varela-Rey, B Mejuto… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The prevalence of obesity has increased considerably in the last few decades.
Pathophysiological changes in obese patients lead to pharmacokinetic (PK) and …

Patients with Obesity Should be Recognised as a Special Patient Population During Drug Development of Antibacterial and Antifungal Agents; A Call to Action

KP van Rhee, CAJ Knibbe, PD van der Linden… - Clinical …, 2024 - Springer
Individuals with obesity are at increased risk of developing infectious diseases. Timely
administration of an effective dose of an antimicrobial agent is paramount to safeguard …

The Effect of Vancomycin and Piperacillin-Tazobactam on Incidence of Acute Kidney Injury in Patients With Obesity

A Wuerger, J Bowden, A Mitchell… - Hospital …, 2023 - journals.sagepub.com
Background: Increasing evidence suggests that administration of combination vancomycin
and piperacillin-tazobactam (VPT) increases the incidence of acute kidney injury (AKI) …

Obesitatearen inpaktua ß-laktamiko antipseudomonikoen portaera farmakozinetiko/farmakodinamikoan paziente kritikoetan. Egokia al da egungo dosifikazioa?

U Etxeberria Iztueta - 2023 - addi.ehu.es
Antibiotikoekiko erresistentzia gora doan honetan, hilkortasun tasa altua duen paziente
kritikoen populazioa aztertu eta hauentzako dosifikazio erregimenik aproposena …

[PDF][PDF] Nomogramm auf Basis der eGFR zur empirischen Dosie-rung von Piperacillin/Tazobac-tam als kontinuierliche Infusion bei kritisch Kranken

A Reimer, S Günther, H Vogl, S Spenke, M Hoffmann… - researchgate.net
Die frühe Antibiotikatherapie ist bei kritisch kranken Patienten entscheidend für das
Outcome. Für Piperacillin, eins der wichtigsten Breitspektrum-Antibiotika der Intensivstation …