[HTML][HTML] Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions

YB Liu, MK Chen - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date
epidemiological features of cirrhosis and its complications. Recent epidemiological studies …

[HTML][HTML] Non-alcoholic fatty liver disease in women–current knowledge and emerging concepts

PC Eng, R Forlano, T Tan, P Manousou, WS Dhillo… - JHEP Reports, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide,
affecting up to 30% of adults. Progression to non-alcoholic steatohepatitis (NASH) is a key …

Detecting liver cancer using cell-free DNA fragmentomes

ZH Foda, AV Annapragada, K Boyapati, DC Bruhm… - Cancer discovery, 2023 - AACR
Liver cancer is a major cause of cancer mortality worldwide. Screening individuals at high
risk, including those with cirrhosis and viral hepatitis, provides an avenue for improved …

[HTML][HTML] Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort

JA Goodrich, D Walker, X Lin, H Wang, T Lim… - JHEP Reports, 2022 - Elsevier
Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …

Hepcidin in hepatocellular carcinoma

JH Joachim, KJ Mehta - British Journal of Cancer, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common reasons for cancer-related
deaths. Excess iron increases HCC risk. Inevitably, hepcidin, the iron hormone that …

Nonalcoholic liver disease: epidemiology, risk factors, natural history, and management strategies

G Agyapong, F Dashti, BA Banini - … of the New York Academy of …, 2023 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease
worldwide and a leading indication for liver transplantation in the United States. NAFLD …

Screening for NAFLD—current knowledge and challenges

R Forlano, G Sigon, BH Mullish, M Yee, P Manousou - Metabolites, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver
function tests worldwide, with an estimated prevalence ranging between 19–46% in the …

MicroRNA-483-5p inhibits hepatocellular carcinoma cell proliferation, cell steatosis, and fibrosis by targeting PPARα and TIMP2

S Niture, S Gadi, Q Qi, MA Gyamfi, RS Varghese… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the fifth leading and highly aggressive
lethal liver cancer. The most common cause of HCC is liver cirrhosis because of multiple …

Should we undertake surveillance for HCC in patients with MAFLD?

B Norero, JF Dufour - Therapeutic Advances in …, 2023 - journals.sagepub.com
Over the last decade, metabolic-associated fatty liver disease (MAFLD) has become an
important public health issue worldwide. In many countries, MAFLD has become the most …

[HTML][HTML] Metabolic primary liver cancer in adults: risk factors and pathogenic mechanisms

S Lugari, E Baldelli, A Lonardo - Metabolism and Target Organ …, 2023 - oaepublish.com
Primary liver cancer (PLC) is a heterogeneous group of disorders arising with the
background of chronic liver disease (CLD) owing to varying etiologies. PLC carries a high …