Cardiac pacemaker activity and aging
A progressive decline in maximum heart rate (mHR) is a fundamental aspect of aging in
humans and other mammals. This decrease in mHR is independent of gender, fitness, and …
humans and other mammals. This decrease in mHR is independent of gender, fitness, and …
Slowing down as we age: aging of the cardiac pacemaker's neural control
The cardiac pacemaker ignites and coordinates the contraction of the whole heart,
uninterruptedly, throughout our entire life. Pacemaker rate is constantly tuned by the …
uninterruptedly, throughout our entire life. Pacemaker rate is constantly tuned by the …
The effect of age on the heart rate variability of healthy subjects
L Garavaglia, D Gulich, MM Defeo… - PLoS …, 2021 - journals.plos.org
In this work we study the characteristics of heart rate variability (HRV) as a function of age
and gender. Our analysis covers a wider age range than that studied so far. It includes …
and gender. Our analysis covers a wider age range than that studied so far. It includes …
PhysioZoo: a novel open access platform for heart rate variability analysis of mammalian electrocardiographic data
JA Behar, AA Rosenberg, I Weiser-Bitoun… - Frontiers in …, 2018 - frontiersin.org
Background: The time variation between consecutive heartbeats is commonly referred to as
heart rate variability (HRV). Loss of complexity in HRV has been documented in several …
heart rate variability (HRV). Loss of complexity in HRV has been documented in several …
Signatures of the autonomic nervous system and the heart's pacemaker cells in canine electrocardiograms and their applications to humans
AA Rosenberg, I Weiser-Bitoun, GE Billman… - Scientific Reports, 2020 - nature.com
Heart rate and heart rate variability (HRV) are mainly determined by the autonomic nervous
system (ANS), which interacts with receptors on the sinoatrial node (SAN; the heart's primary …
system (ANS), which interacts with receptors on the sinoatrial node (SAN; the heart's primary …
Overexpression of a neuronal type adenylyl cyclase (type 8) in sinoatrial node markedly impacts heart rate and rhythm
JM Moen, MG Matt, C Ramirez, KV Tarasov… - Frontiers in …, 2019 - frontiersin.org
Heart rate (HR) and HR variability (HRV), predictors of over-all organism health, are widely
believed to be driven by autonomic input to the sinoatrial node (SAN), with sympathetic input …
believed to be driven by autonomic input to the sinoatrial node (SAN), with sympathetic input …
[HTML][HTML] Age-related changes in cardiac autonomic modulation and heart rate variability in mice
C Piantoni, L Carnevali, D Molla, A Barbuti… - Frontiers in …, 2021 - frontiersin.org
Objective The aim of this study was to assess age-related changes in cardiac autonomic
modulation and heart rate variability (HRV) and their association with spontaneous and …
modulation and heart rate variability (HRV) and their association with spontaneous and …
Complexities in cardiovascular rhythmicity: perspectives on circadian normality, ageing and disease
O Monfredi, EG Lakatta - Cardiovascular research, 2019 - academic.oup.com
Biological rhythms exist in organisms at all levels of complexity, in most organs and at
myriad time scales. Our own biological rhythms are driven by energy emitted by the sun …
myriad time scales. Our own biological rhythms are driven by energy emitted by the sun …
Altered heart rate variability in angiotensin II–mediated hypertension is associated with impaired autonomic nervous system signaling and intrinsic sinoatrial node …
Background Hypertensive heart disease is associated with sinoatrial node (SAN)
dysfunction and reductions in heart rate variability (HRV). Alterations in HRV could occur in …
dysfunction and reductions in heart rate variability (HRV). Alterations in HRV could occur in …
Aging alters the formation and functionality of signaling microdomains between L-type calcium channels and β2-adrenergic receptors in cardiac pacemaker cells
Heart rate is accelerated to match physiological demands through the action of
noradrenaline on the cardiac pacemaker. Noradrenaline is released from sympathetic …
noradrenaline on the cardiac pacemaker. Noradrenaline is released from sympathetic …