Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

The intracellular parasite Toxoplasma gondii has long provided a tractable experimental
system to investigate how the immune system deals with intracellular infections. This review …

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

Highlights•Toxoplasma gondii evokes a strong innate and adaptive immune response in the
host.•Innate immunity to the parasite is comprised of many components like DC, neutrophils …

To define cellular immunity to the intracellular pathogen Toxoplasma gondii, we performed a
genome-wide CRISPR loss-of-function screen to identify genes important for (interferon …

The physical barrier of the intestine and associated mucosal immunity maintains a delicate
homeostatic balance between the host and the external environment by regulating immune …

Upon pathogen detection, macrophages normally stay sessile in tissues while dendritic cells
(DCs) migrate to secondary lymphoid tissues. The obligate intracellular protozoan …

Toxoplasma gondii is an obligate intracellular parasite that chronically infects a third of
humans. It can cause life-threatening encephalitis in immune-compromised individuals …

The obligate intracellular parasite Toxoplasma gondii secretes a vast variety of effector
molecules from organelles known as rhoptries (ROPs) and dense granules (GRAs). ROP …

Like many intracellular pathogens, the protozoan parasite Toxoplasma gondii has evolved
sophisticated mechanisms to promote its transmission and persistence in a variety of hosts …