Methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl) are coenzymes for methionine
synthase and methylmalonyl‐CoA mutase, respectively. Hydroxylcobalamin (HOCbl) and …

Mercury, cadmium, arsenic and lead are among priority metals for toxicological studies due
to the frequent human exposure and to the significant burden of disease following acute and …

Oxidative stress is a feature of many chronic inflammatory diseases. Such diseases are
associated with up-regulation of a vitamin B12 (cobalamin) blood transport protein and its …

Objective This study had 3 objectives:(1) To summarize and compare assimilation pathways
for 4 B 12 forms;(2) to determine whether supplementation with a particular B 12 form (or …

A comprehensive review on redox reactions of Co (III), Co (II) and Co (I) forms of cobalamins
(vitamin B12) and their derivatives (cobinamide, cobyrinates) is presented. An influence of …

The inorganic chemistry of the cobalt corrinoids, derivatives of vitamin B 12, is reviewed, with
particular emphasis on equilibrium constants for, and kinetics of, their axial ligand …

Many coenzymes are vitamins that are assimilated in mammals into their active form from
precursors obtained from the diet. They are often both rare and reactive rendering the …

We report a kinetic study of the reaction between superoxide and an important intracellular
form of vitamin B12, cob (II) alamin. Superoxide is implicated in the pathophysiology of many …

Cobalamins are important cofactors for methionine synthase and methylmalonyl-CoA
mutase. Certain corrins also bind nitric oxide (NO), quenching its bioactivity. To determine if …

Background Methylmalonic aciduria with homocystinuria, cblC defect, is the most frequent
disorder of vitamin B12 metabolism. CblC patients are commonly treated with a multidrug …