Lipid-based nanoparticles in the clinic and clinical trials: from cancer nanomedicine to COVID-19 vaccines

TTH Thi, EJA Suys, JS Lee, DH Nguyen, KD Park… - Vaccines, 2021 - mdpi.com
COVID-19 vaccines have been developed with unprecedented speed which would not have
been possible without decades of fundamental research on delivery nanotechnology. Lipid …

[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Application of advanced emulsion technology in the food industry: A review and critical evaluation

C Tan, DJ McClements - Foods, 2021 - mdpi.com
The food industry is one of the major users of emulsion technology, as many food products
exist in an emulsified form, including many dressings, sauces, spreads, dips, creams, and …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Deep eutectic solvents: Recent advances in fabrication approaches and pharmaceutical applications

Y Liu, Y Wu, J Liu, W Wang, Q Yang, G Yang - International Journal of …, 2022 - Elsevier
Deep eutectic solvents (DESs) have received increasing attention in the past decade owing
to their distinguished properties including biocompatibility, tunability, thermal and chemical …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) as food-grade nanovehicles for hydrophobic nutraceuticals or bioactives

CH Tang, HL Chen, JR Dong - Applied Sciences, 2023 - mdpi.com
Although solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have
been successfully used as drug delivery systems for about 30 years, the usage of these …

Nanocarriers transport across the gastrointestinal barriers: the contribution to oral bioavailability via blood circulation and lymphatic pathway

D Wang, Q Jiang, Z Dong, T Meng, F Hu, J Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …

A review on chemical and physical modifications of phytosterols and their influence on bioavailability and safety

S Feng, L Wang, P Shao, P Sun… - Critical reviews in food …, 2022 - Taylor & Francis
Phytosterols have been shown to lower cholesterol levels and to have antioxidant, anti-
inflammatory and other biological activities. However, the high melting point and poor …