Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] Loading recommendations for muscle strength, hypertrophy, and local endurance: a re-examination of the repetition continuum

BJ Schoenfeld, J Grgic, DW Van Every, DL Plotkin - Sports, 2021 - mdpi.com
Sports | Free Full-Text | Loading Recommendations for Muscle Strength, Hypertrophy, and
Local Endurance: A Re-Examination of the Repetition Continuum Next Article in Journal …

Resistance training recommendations to maximize muscle hypertrophy in an athletic population: Position stand of the IUSCA

B Schoenfeld, J Fisher, J Grgic, C Haun… - … Journal of Strength …, 2021 - journal.iusca.org
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of
a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle …

[HTML][HTML] A critical evaluation of the biological construct skeletal muscle hypertrophy: size matters but so does the measurement

CT Haun, CG Vann, BM Roberts, AD Vigotsky… - Frontiers in …, 2019 - frontiersin.org
Skeletal muscle is highly adaptable and has consistently been shown to morphologically
respond to exercise training. Skeletal muscle growth during periods of resistance training …

Muscle fibre activation is unaffected by load and repetition duration when resistance exercise is performed to task failure

RW Morton, MW Sonne, A Farias Zuniga… - The Journal of …, 2019 - Wiley Online Library
Key points Performing resistance exercise with heavier loads is often proposed to be
necessary for the recruitment of larger motor units and activation of type II muscle fibres …

The three-month effects of a ketogenic diet on body composition, blood parameters, and performance metrics in CrossFit trainees: a pilot study

WC Kephart, CD Pledge, PA Roberson, PW Mumford… - Sports, 2018 - mdpi.com
Adopting low carbohydrate, ketogenic diets remains a controversial issue for individuals
who resistance train given that this form of dieting has been speculated to reduce skeletal …

Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men

CL Sexton, JS Godwin, MC McIntosh, BA Ruple… - Cells, 2023 - mdpi.com
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …

Pre-training skeletal muscle fiber size and predominant fiber type best predict hypertrophic responses to 6 weeks of resistance training in previously trained young …

CT Haun, CG Vann, CB Mobley, SC Osburn… - Frontiers in …, 2019 - frontiersin.org
Limited evidence exists regarding differentially expressed biomarkers between previously-
trained low versus high hypertrophic responders in response to resistance training. Herein …

[HTML][HTML] Resistance training increases muscle NAD+ and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight …

DA Lamb, JH Moore, PHC Mesquita, MA Smith… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
We examined if resistance training affected muscle NAD+ and NADH concentrations as well
as nicotinamide phosphoribosyltransferase (NAMPT) protein levels and sirtuin (SIRT) …

[HTML][HTML] Effects of graded whey supplementation during extreme-volume resistance training

CT Haun, CG Vann, CB Mobley, PA Roberson… - Frontiers in …, 2018 - frontiersin.org
We examined hypertrophic outcomes of weekly graded whey protein dosing (GWP) versus
whey protein (WP) or maltodextrin (MALTO) dosed once daily during 6 weeks of high …