Present and future of the diagnostic work-up of multiple sclerosis: the imaging perspective

M Filippi, P Preziosa, DL Arnold, F Barkhof… - Journal of …, 2023 - Springer
In recent years, the use of magnetic resonance imaging (MRI) for the diagnostic work-up of
multiple sclerosis (MS) has evolved considerably. The 2017 McDonald criteria show high …

MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond

B Vachha, SY Huang - European radiology experimental, 2021 - Springer
Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient
technology has provided enormous gains in sensitivity, resolution, and contrast for …

7T MRI differentiates remyelinated from demyelinated multiple sclerosis lesions

H Kolb, M Absinta, ES Beck, SK Ha, Y Song… - Annals of …, 2021 - Wiley Online Library
Objective To noninvasively assess myelin status in chronic white matter lesions of multiple
sclerosis (MS), we developed and evaluated a simple classification scheme based on T1 …

An anomaly detection approach to identify chronic brain infarcts on MRI

KM Van Hespen, JJM Zwanenburg, JW Dankbaar… - Scientific Reports, 2021 - nature.com
The performance of current machine learning methods to detect heterogeneous pathology is
limited by the quantity and quality of pathology in medical images. A possible solution is …

[HTML][HTML] Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues

F La Rosa, M Wynen, O Al-Louzi, ES Beck… - NeuroImage: Clinical, 2022 - Elsevier
The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …

Simultaneous lesion and brain segmentation in multiple sclerosis using deep neural networks

R McKinley, R Wepfer, F Aschwanden, L Grunder… - Scientific reports, 2021 - nature.com
Segmentation of white matter lesions and deep grey matter structures is an important task in
the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we …

The clinical utility of magnetic resonance imaging according to field strength, specifically addressing the breadth of current state-of-the-art systems, which include 0.55 …

VM Runge, JT Heverhagen - Investigative radiology, 2022 - journals.lww.com
This review provides a balanced perspective regarding the clinical utility of magnetic
resonance systems across the range of field strengths for which current state-of-the-art units …

Automatic segmentation of white matter hyperintensities: validation and comparison with state-of-the-art methods on both Multiple Sclerosis and elderly subjects

P Tran, U Thoprakarn, E Gourieux, CL Dos Santos… - NeuroImage: Clinical, 2022 - Elsevier
Different types of white matter hyperintensities (WMH) can be observed through MRI in the
brain and spinal cord, especially Multiple Sclerosis (MS) lesions for patients suffering from …

New prospects for ultra-high-field magnetic resonance imaging in multiple sclerosis

BV Ineichen, ES Beck, M Piccirelli… - Investigative …, 2021 - journals.lww.com
There is growing interest in imaging multiple sclerosis (MS) through the ultra-high-field
(UHF) lens, which currently means a static magnetic field strength of 7 T or higher. Because …

[HTML][HTML] Age-related changes in relaxation times, proton density, myelin, and tissue volumes in adult brain analyzed by 2-dimensional quantitative synthetic magnetic …

A Hagiwara, K Fujimoto, K Kamagata… - Investigative …, 2021 - journals.lww.com
Objectives Quantitative synthetic magnetic resonance imaging (MRI) enables the
determination of fundamental tissue properties, namely, T1 and T2 relaxation times and …