Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Mesenchymal stem cells and their microenvironment

J Liu, J Gao, Z Liang, C Gao, Q Niu, F Wu… - Stem Cell Research & …, 2022 - Springer
Mesenchymal stem cells (MSCs), coming from a wide range of sources, have multi-
directional differentiation ability. MSCs play vital roles in immunomodulation, hematopoiesis …

Recent advances to enhance the immunomodulatory potential of mesenchymal stem cells

M Sarsenova, Y Kim, K Raziyeva, B Kazybay… - Frontiers in …, 2022 - frontiersin.org
Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including
their immunosuppressive and immunomodulatory properties as well as their ability to …

Current strategies to enhance adipose stem cell function: an update

Y Seo, TH Shin, HS Kim - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …

Injectable hypoxia-induced conductive hydrogel to promote diabetic wound healing

X Jin, Y Shang, Y Zou, M Xiao, H Huang… - … Applied Materials & …, 2020 - ACS Publications
Injectable hydrogels with the capability to cast a hypoxic microenvironment is of great
potentialities to develop novel therapies for tissue regeneration. However, the relative …

Antioxidants inhibit cell senescence and preserve stemness of adipose tissue-derived stem cells by reducing ROS generation during long-term in vitro expansion

N Liao, Y Shi, C Zhang, Y Zheng, Y Wang… - Stem cell research & …, 2019 - Springer
Background Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising
candidates for regenerative medicine. However, long-term in vitro passaging leads to …

[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …

Cause and consequence of heterogeneity in human mesenchymal stem cells: Challenges in clinical application

Z Lyu, M Xin, DR Oyston, T Xue, H Kang… - … -Research and Practice, 2024 - Elsevier
Human mesenchymal stem cells (hMSCs) are mesoderm-derived adult stem cells with self-
proliferation capacity, pluripotent differentiation potency, and excellent histocompatibility …

Mesenchymal stromal cells: heterogeneity and therapeutical applications

M Ouzin, G Kogler - Cells, 2023 - mdpi.com
Mesenchymal stromal cells nowadays emerge as a major player in the field of regenerative
medicine and translational research. They constitute, with their derived products, the most …

Effects of mechanical loading on human mesenchymal stem cells for cartilage tissue engineering

JR Choi, KW Yong, JY Choi - Journal of cellular physiology, 2018 - Wiley Online Library
Today, articular cartilage damage is a major health problem, affecting people of all ages.
The existing conventional articular cartilage repair techniques, such as autologous …