Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

Importance Early identification of cognitive impairment may improve patient and caregiver
health outcomes. Objective To systematically review the test accuracy of cognitive screening …

This article argues that it is still premature to start widespread screening for adverse
childhood experiences (ACE) in health care settings until we have answers to several …

Background The Mini Mental State Examination (MMSE) is a cognitive test that is commonly
used as part of the evaluation for possible dementia. Objectives To determine the diagnostic …

Importance Cognitive decline is a common and feared aspect of aging. Mild cognitive
impairment (MCI) is defined as the symptomatic predementia stage on the continuum of …

Trisha Greenhalgh and colleagues argue that, although evidence based medicine has had
many benefits, it has also had some negative unintended consequences. They offer a …

Alzheimer's disease is a progressive neurodegenerative disease that typically manifests
clinically as an isolated amnestic deficit that progresses to a characteristic dementia …

The increase in life expectancy has resulted in a high occurrence of dementia and
Alzheimer's disease (AD). Research on AD has undergone a paradigm shift from viewing it …

Dementia with Lewy bodies (DLB) is the second most common type of degenerative
dementia following Alzheimer's disease (AD). DLB is clinically and pathologically related to …

Population aging is among the most important global transformations. Today, 12% of the
world population is of age 60 and over and by the middle of this century this segment will …