Mechanisms of ammonia-induced astrocyte swelling

MD Norenberg, KVR Rao, AR Jayakumar - Metabolic brain disease, 2005 - Springer
Astrocyte swelling represents the major factor responsible for the brain edema associated
with fulminant hepatic failure (FHF). The edema may be of such magnitude as to increase …

Clinicoepidemiological, toxicological, and safety evaluation studies on argemone oil

M Das, SK Khanna - Critical reviews in toxicology, 1997 - Taylor & Francis
Consumption of oil extracted from accidental or deliberate contamination of argemone seed
to mustard seed is known to pose a clinical condition popularly referred to as Epidemic …

Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment

P Kosina, D Walterova, J Ulrichová… - Food and Chemical …, 2004 - Elsevier
Sanguinaria canadesis, Chelidonium majus and Macleya cordata have been used for
centuries as alternative medicines. Currently the extracts from these medicinal plants are …

Riboflavin induces disease resistance in plants by activating a novel signal transduction pathway

H Dong, SV Beer - Phytopathology, 2000 - Am Phytopath Society
The role of riboflavin as an elicitor of systemic resistance and an activator of a novel
signaling process in plants was demonstrated. Following treatment with riboflavin …

Riboflavin‐induced Priming for Pathogen Defense in Arabidopsis thaliana

S Zhang, X Yang, M Sun, F Sun… - Journal of Integrative …, 2009 - Wiley Online Library
Riboflavin (vitamin B2) participates in a variety of redox processes that affect plant defense
responses. Previously we have shown that riboflavin induces pathogen resistance in the …

Oxidative stress in the pathogenesis of hepatic encephalopathy

MD Norenberg, AR Jayakumar, KV Rama Rao - Metabolic brain disease, 2004 - Springer
The pathogenesis of hepatic encephalopathy (HE) remains elusive. While it is clear that
ammonia is the likely toxin and that astrocytes are the main target of its neurotoxicity …

Epidemic dropsy in India

BD Sharma, S Malhotra, V Bhatia… - Postgraduate medical …, 1999 - academic.oup.com
Epidemic dropsy is a clinical state resulting from use of edible oils adulterated with
Argemone mexicana oil. Sanguinarine and dehydrosanguinarine are two major toxic …

In vivo DNA damaging potential of sanguinarine alkaloid, isolated from argemone oil, using alkaline Comet assay in mice

KM Ansari, A Dhawan, SK Khanna, M Das - Food and chemical toxicology, 2005 - Elsevier
Consumption of mustard oil contaminated with argemone oil is well known to cause clinical
manifestation referred to as “Epidemic Dropsy”. Our prior studies have shown that argemone …

Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy

C Bemeur, P Desjardins, RF Butterworth - Metabolic brain disease, 2010 - Springer
Hepatic encephalopathy (HE) is a serious complication of liver failure. HE manifests as a
series of neuropsychiatric and neuromuscular symptoms including personality changes …

Oxidative damage of plasma proteins and lipids in epidemic dropsy patients: alterations in antioxidant status

M Das, K Babu, NP Reddy, LM Srivastava - Biochimica et Biophysica Acta …, 2005 - Elsevier
Epidemic dropsy is an acute food adulterant disease caused due to consumption of edible
mustard oil contaminated with argemone oil. Our in vitro studies have shown that the toxicity …