Genetic testing in pediatric kidney disease

V Arora, K Anand, I Chander Verma - The Indian Journal of Pediatrics, 2020 - Springer
The advent of next gene sequencing technology has led to the publication of a profusion of
papers on monogenic contributions to pediatric kidney disorders. It started with the discovery …

[PDF][PDF] Steroid resistant nephrotic syndrome-genetic consideration

V Tasic, Z Gucev, M Polenakovic - prilozi, 2015 - sciendo.com
Nephrotic syndrome is defined as the association of massive proteinuria,
hypoalbuminaemia, edema, and hyperlipidemia. It is separated to steroid-sensitive or …

Metabolomics coupled with integrative pharmacology reveal the protective effect of FangjiHuangqi Decoction against adriamycin-induced rat nephropathy model

WN Zhang, L Yang, SS He, XM Qin, AP Li - Journal of pharmaceutical and …, 2019 - Elsevier
With the development of the society, the number of people who got the nephrotic syndrome
(NS) is going up roughly. Therefore, finding a better way to treat NS is becoming a major …

WT1 and NPHS2 gene mutation analysis and clinical management of steroid-resistant nephrotic syndrome

ASK Ramanathan, M Vijayan, S Rajagopal… - Molecular and cellular …, 2017 - Springer
Nephrotic syndrome (NS) is a kidney disease predominantly present in children with
idiopathic condition; final stage of the disease progresses into end-stage renal disease …

Spectrum of NPHS1 and NPHS2 variants in egyptian children with focal segmental glomerular sclerosis: identification of six novel variants and founder effect

MM Thomas, HM Ahmed, SH El-Dessouky… - Molecular Genetics and …, 2022 - Springer
The aim of this study is to screen for variants in NPHS1 and NPHS2, in a cohort of Egyptian
children with steroid-resistant nephrotic syndrome (SRNS)/focal segmental …

High Serum Endothelin-1 Level is Associated with Poor Response to Steroid Therapy in Childhood-Onset Nephrotic Syndrome

HM Ahmed, DS Morgan, NA Doudar… - Saudi Journal of Kidney …, 2019 - journals.lww.com
Nephrotic syndrome (NS) is one of the most common kidney diseases seen in children. It is
a disorder characterized by severe proteinuria, hypoproteinemia, hyperlipidemia, and …

NPHS2 Mutations: A Closer Look to Latin American Countries

MS Guaragna, ACGB Lutaif… - BioMed Research …, 2017 - Wiley Online Library
Nephrotic syndrome is one of the most common kidney pathologies in childhood, being
characterized by proteinuria, edema, and hypoalbuminemia. In clinical practice, it is divided …

Cytokine gene polymorphisms in Chinese children with idiopathic nephrotic syndrome

W Li, L Li, L He, Y Du, HD Fu, ZY Peng… - Iranian Journal of …, 2022 - iji.sums.ac.ir
Background: Cytokines play a role in the progression of idiopathic-nephrotic syndrome
(INS). Objectives: To investigate the association of different cytokine genes polymorphisms …

[HTML][HTML] Genetic mutation in Egyptian children with steroid-resistant nephrotic syndrome

MM Thomas, MS Abdel-Hamid, NN Mahfouz… - Journal of the Formosan …, 2018 - Elsevier
Abstract Background/Purpose Nephrotic syndrome is the commonest etiology of proteinuria
in children. Steroid-resistant nephrotic syndrome (SRNS) is defined by resistance to …

Characterization of NPHS2 gene polymorphisms associated to steroid resistance nephrotic syndrome in Indian children

BB Joshi, KN Mistry, S Gang, PG Koringa, CG Joshi - Gene, 2017 - Elsevier
Nephrotic syndrome (NS) is the common glomerular disease in children. These children are
treated with steroids, depending upon their behavior. They are either steroid sensitive …