Histidine is a dietary essential amino acid because it cannot be synthesized in humans. The
WHO/FAO requirement for adults for histidine is 10 mg· kg body weight-1· d-1. Histidine is …

Large-scale genomic investigations have just begun to illuminate the molecular genetic
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …

Loss of dopamine in Parkinson's disease is hypothesized to impede movement by inducing
hypo-and hyperactivity in striatal spiny projection neurons (SPNs) of the direct (dSPNs) and …

In vertebrates, during an early wave of hematopoiesis in the yolk sac between embryonic
day E7. 0 and E9. 0, cells of mesodermal leaflet addressed to macrophage lineage enter in …

Among the four G protein–coupled receptors (H1–H4) identified as mediators of the biologic
effects of histamine, the H3 receptor (H3R) is distinguished for its almost exclusive …

Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder
that is characterized by several motor and phonic tics. Tics usually develop before 10 years …

Our 1992 paper,'The neural substrates of sensorimotor gating of the startle reflex: a review of
recent findings and their implications', reviewed a series of (then) new and preliminary …

Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …

Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter
and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the …

Tic disorders (TD) are a group neuropsychiatric disorders with childhood onset
characterized by tics, ie repetitive, sudden, and involuntary movements or vocalizations; and …