Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

Enteric viruses, particularly rotaviruses and noroviruses, are a leading cause of
gastroenteritis worldwide. Rotaviruses primarily affect young children, accounting for almost …

Background Since licensure in 2006, rotavirus vaccines have been introduced in more than
100 countries. The efficacy of rotavirus vaccines is variable in settings with different child …

The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Diarrheal disease is characterized by the onset of loose stools with or without vomiting,
which may be associated with systemic manifestations, such as fever and abdominal …

Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

Vaccines are the most effective means available for preventing infectious diseases.
However, vaccine-induced immune responses are highly variable between individuals and …

Human gastrointestinal tract research is limited by the paucity of in vitro intestinal cell
models that recapitulate the cellular diversity and complex functions of human physiology …

Background WHO recommends routine use of rotavirus vaccines in all countries, particularly
in those with high mortality attributable to diarrhoeal diseases. To establish the burden of life …

Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …