Interactions between metal oxides and biomolecules: from fundamental understanding to applications

MJ Limo, A Sola-Rabada, E Boix, V Thota… - Chemical …, 2018 - ACS Publications
Metallo-oxide (MO)-based bioinorganic nanocomposites promise unique structures,
physicochemical properties, and novel biochemical functionalities, and within the past …

Solid-binding proteins: bridging synthesis, assembly, and function in hybrid and hierarchical materials fabrication

K Pushpavanam, J Ma, Y Cai, NY Naser… - Annual Review of …, 2021 - annualreviews.org
There is considerable interest in the development of hybrid organic–inorganic materials
because of the potential for harvesting the unique capabilities that each system has to offer …

Protein conformational changes at the oil/water-interface induced by premix membrane emulsification

T Wollborn, M Michaelis, LC Ciacchi… - Journal of Colloid and …, 2022 - Elsevier
We present combined experimental and modelling evidence that β-lactoglobulin proteins
employed as stabilizers of oil/water emulsions undergo minor but significant conformational …

Controlling the multiscale structure of nanofibrous fibrinogen scaffolds for wound healing

K Stapelfeldt, S Stamboroski, I Walter, N Suter… - Nano …, 2019 - ACS Publications
As a key player in blood coagulation and tissue repair, fibrinogen has gained increasing
attention to develop nanofibrous biomaterial scaffolds for wound healing. Current …

[HTML][HTML] Poly-sarcosine and poly (ethylene-glycol) interactions with proteins investigated using molecular dynamics simulations

G Settanni, T Schäfer, C Muhl, M Barz… - Computational and …, 2018 - Elsevier
Nanoparticles coated with hydrophilic polymers often show a reduction in unspecific
interactions with the biological environment, which improves their biocompatibility. The …

Shielding and stealth effects of zwitterion moieties in double-functionalized silica nanoparticles

LMD Loiola, M Batista, LB Capeletti, GB Mondo… - Journal of colloid and …, 2019 - Elsevier
Surface functionalization of silica nanoparticles (SiO 2 NPs) has been considered as a
promising strategy to develop target-specific nanostructures. However, finding a chemical …

[HTML][HTML] Formation mechanisms of chitosan-silica hybrid materials and its performance as solid support for KR-12 peptide adsorption: Impact on KR-12 antimicrobial …

J Diosa, F Guzman, C Bernal, M Mesa - Journal of Materials Research and …, 2020 - Elsevier
Chitosan-silica materials offer a specific environment for the adsorption of biofunctional
molecules, such as the antimicrobial peptide KR-12. The objective here is to rationalize the …

[HTML][HTML] Bare silica as an alternative matrix for affinity purification/immobilization of His-tagged proteins

AI Freitas, L Domingues, TQ Aguiar - Separation and Purification …, 2022 - Elsevier
Abstract “Green” protein purification/immobilization processes based on low-cost, earth-
abundant, and eco-friendly affinity matrices are highly desirable. Unmodified silica matrices …

Arrested in glass: actin within sophisticated architectures of biosilica in sponges

H Ehrlich, M Luczak, R Ziganshin, I Mikšík… - Advanced …, 2022 - Wiley Online Library
Actin is a fundamental member of an ancient superfamily of structural intracellular proteins
and plays a crucial role in cytoskeleton dynamics, ciliogenesis, phagocytosis, and force …

Atomistic details of chymotrypsin conformational changes upon adsorption on silica

N Hildebrand, M Michaelis, N Wurzler, Z Li… - ACS Biomaterials …, 2018 - ACS Publications
Adsorption of enzymes on solid surfaces may lead to conformational changes that reduce
their catalytic conversion activity and are thus detrimental to the efficiency of biotechnology …