Immunity and inflammation in atherosclerosis

D Wolf, K Ley - Circulation research, 2019 - Am Heart Assoc
There is now overwhelming experimental and clinical evidence that atherosclerosis is a
chronic inflammatory disease. Lessons from genome-wide association studies, advanced in …

Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas

A Zernecke, H Winkels, C Cochain… - Circulation …, 2020 - Am Heart Assoc
The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

The immunology of atherosclerosis

A Gisterå, GK Hansson - Nature reviews nephrology, 2017 - nature.com
Cardiovascular disease is the leading cause of death worldwide, both in the general
population and among patients with chronic kidney disease (CKD). In most cases, the …

New insights into the role of inflammation in the pathogenesis of atherosclerosis

MY Wu, CJ Li, MF Hou, PY Chu - International journal of molecular …, 2017 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local …

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
Atherosclerosis is an inflammatory disease within the arterial wall that is responsible for
several important adverse vascular events, including coronary artery disease, myocardial …

Inflammation in atherosclerosis

P Libby - Arteriosclerosis, thrombosis, and vascular biology, 2012 - Am Heart Assoc
Experimental work has elucidated molecular and cellular pathways of inflammation that
promote atherosclerosis. Unraveling the roles of cytokines as inflammatory messengers …

The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

Progress and challenges in translating the biology of atherosclerosis

P Libby, PM Ridker, GK Hansson - Nature, 2011 - nature.com
Atherosclerosis is a chronic disease of the arterial wall, and a leading cause of death and
loss of productive life years worldwide. Research into the disease has led to many …

Inflammation as a therapeutic target in atherosclerosis

MT Nguyen, S Fernando, N Schwarz, JTM Tan… - Journal of clinical …, 2019 - mdpi.com
Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

Immune effector mechanisms implicated in atherosclerosis: from mice to humans

P Libby, AH Lichtman, GK Hansson - Immunity, 2013 - cell.com
According to the traditional view, atherosclerosis results from a passive buildup of
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …