The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Complex multicellular organisms require a coordinated response from multiple tissues to
maintain whole-body homeostasis in the face of energetic stressors such as fasting, cold …

The world population is aging, leading to increased rates of neurodegenerative disorders.
Exercise has countless health benefits and has consistently been shown to improve brain …

Repeated activation of the beta 3 adrenergic receptor (β3AR) with the agonist CL 316,243
(CL) results in remodeling of white adipose tissue (WAT) characterized by increased …

Olanzapine is a second-generation antipsychotic (SGA) used frequently in the treatment of
schizophrenia and a growing list of off-label conditions. Though effective in reducing …

Due to excess energy intake and a sedentary lifestyle, the prevalence of obesity is rising
steadily and has emerged as a global public health problem. Adipose tissue undergoes …

Non-alcoholic fatty liver disease (NAFLD) is associated with several metabolic
comorbidities, and the excessive accumulation of hepatic lipids is strongly related to both …

Skeletal muscle is the largest tissue that modulates metabolic homeostasis with metabolic
cross-talk caused by various myokines. The purpose of this study was to investigate the …

Today's elite athletes train year-round and expend huge amounts of energy daily.
Consequently, dietary recommendations must differ substantially compared to their …

Exercise induces beneficial adaptations in virtually every tissue and cell in the body. While
the benefits of exercise were originally thought to arise from local effects, at least in skeletal …