Chemical modifications in nucleic acids for therapeutic and diagnostic applications

C Fàbrega, A Aviñó, R Eritja - The Chemical Record, 2022 - Wiley Online Library
The last decade has witnessed the blooming of nucleic acids for therapeutic and diagnostic
applications. In the present article, we describe the most important results from our group in …

[HTML][HTML] RNase H-sensitive multifunctional ASO-based constructs as promising tools for the treatment of multifactorial complex pathologies

A Mata-Ventosa, A Vila-Planas, A Solsona-Pujol… - Bioorganic …, 2024 - Elsevier
Combined therapies play a key role in the fight against complex pathologies, such as cancer
and related drug-resistance issues. This is particularly relevant in targeted therapies where …