Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019 - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Kaposi's sarcoma

K Antman, Y Chang - New England Journal of Medicine, 2000 - Mass Medical Soc
In 1872, Moritz Kaposi, a Hungarian dermatologist, described five men with aggressive
“idiopathic multiple pigmented sarcomas of the skin.” 1 One patient died of gastrointestinal …

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

JJ Russo, RA Bohenzky, MC Chien… - Proceedings of the …, 1996 - National Acad Sciences
The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped
with cosmid and phage genomic libraries from the BC-1 cell line. Its nucleotide sequence …

Malignancy after transplantation

JF Buell, TG Gross, ES Woodle - Transplantation, 2005 - journals.lww.com
As newer immunosuppressive regimens have steadily reduced the incidence of acute
rejection and have extended the life expectancy of allograft recipients, posttransplant …

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

ME Ballestas, PA Chatis, KM Kaye - Science, 1999 - science.org
Primary effusion lymphoma (PEL) cells harbor Kaposi's sarcoma–associated herpesvirus
(KSHV) episomes and express a KSHV-encoded latency-associated nuclear antigen …

Spectrum of AIDS-associated malignant disorders

JJ Goedert, TR Coté, P Virgo, SM Scoppa, DW Kingma… - The Lancet, 1998 - thelancet.com
Background To clarify which types of cancer result from AIDS, we compared the cancer
experiences of people with AIDS with those of the general population by matching …

Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

R Renne, W Zhong, B Herndier, M Mcgrath, N Abbey… - Nature medicine, 1996 - nature.com
Kaposi's sarcoma (KS) is the leading neoplasm of AIDS patients, and HIV infection is known
to be a major risk factor for its development1, 2. However, KS can occur in the absence of …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus

R Sun, SF Lin, L Gradoville, Y Yuan… - Proceedings of the …, 1998 - National Acad Sciences
Herpesviruses exist in two states, latency and a lytic productive cycle. Here we identify an
immediate-early gene encoded by Kaposi's sarcoma-associated herpesvirus (KSHV)/human …

KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

SJ Gao, L Kingsley, M Li, W Zheng, C Parravicini… - Nature medicine, 1996 - nature.com
A major controversy regarding Kaposi's sarcoma–associated herpesvirus (KSHV or HHV8)
1, 2 is whether or not it is a ubiquitous infection of humans3, 4. Immunoassays based on …