An overview on promising somatic cell sources utilized for the efficient generation of induced pluripotent stem cells
A Ray, JM Joshi, PK Sundaravadivelu, K Raina… - Stem Cell Reviews and …, 2021 - Springer
Abstract Human induced Pluripotent Stem Cells (iPSCs) have enormous potential in
understanding developmental biology, disease modeling, drug discovery, and regenerative …
understanding developmental biology, disease modeling, drug discovery, and regenerative …
[HTML][HTML] Development of pathophysiologically relevant models of sickle cell disease and β-thalassemia for therapeutic studies
Ex vivo cellular system that accurately replicates sickle cell disease and β-thalassemia
characteristics is a highly sought-after goal in the field of erythroid biology. In this study, we …
characteristics is a highly sought-after goal in the field of erythroid biology. In this study, we …
Development of an efficient single-cell cloning and expansion strategy for genome edited induced pluripotent stem cells
N Bhargava, P Thakur, TP Muruganandam… - Molecular Biology …, 2022 - Springer
Background Disease-specific human induced pluripotent stem cells (hiPSCs) can be
generated directly from individuals with known disease characteristics or alternatively be …
generated directly from individuals with known disease characteristics or alternatively be …
[HTML][HTML] Reprogramming of a human induced pluripotent stem cell line from one 48-year-old healthy male donor
R Guo, W Mu, X Liu, J Zhang, B Liu, X Du, J He, J Ma… - Stem Cell Research, 2021 - Elsevier
In this study, skin biopsy was collected from a healthy 48-year old male donor with informed
consent, and the fibroblasts were isolated from the dermal explant cultures. Here, a human …
consent, and the fibroblasts were isolated from the dermal explant cultures. Here, a human …