Exploration of the sialic acid world

R Schauer, JP Kamerling - Advances in carbohydrate chemistry and …, 2018 - Elsevier
Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Toward automated enzymatic synthesis of oligosaccharides

L Wen, G Edmunds, C Gibbons, J Zhang… - Chemical …, 2018 - ACS Publications
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Antiviral polymers: past approaches and future possibilities

RH Bianculli, JD Mase, MD Schulz - Macromolecules, 2020 - ACS Publications
Treating a viral disease is no simple feat. Drug resistance, latent reservoirs in the body,
emerging novel viruses, and a frequent lack of specific treatments all complicate antiviral …

En route to the transformation of glycoscience: A chemist's perspective on internal and external crossroads in glycochemistry

D Crich - Journal of the American Chemical Society, 2020 - ACS Publications
Carbohydrate chemistry is an essential component of the glycosciences and is fundamental
to their progress. This Perspective takes the position that carbohydrate chemistry, or …

Advances in the biology and chemistry of sialic acids

X Chen, A Varki - ACS chemical biology, 2010 - ACS Publications
Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.
Natural existing sialic acid-containing structures are presented in different sialic acid forms …

Toward automated oligosaccharide synthesis

CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

Assignment of the absolute configuration of polyfunctional compounds by NMR using chiral derivatizing agents

JM Seco, E Quiñoá, R Riguera - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION AND SCOPE Interest in determining the absolute stereochemistry of a
chiral organic compound stems from the widely recognized fact that the stereochemistry …

[HTML][HTML] Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Unnatural α2, 6-Linked Sialosides: A P. damsela α2, 6-Sialyltransferase with Extremely …

H Yu, S Huang, H Chokhawala, M Sun… - … (International ed. in …, 2006 - ncbi.nlm.nih.gov
Sialic acids are a family of α-keto acids with a 9-carbon backbone. They have been
predominantly found as terminal carbohydrate units on glycoproteins and glycolipids of …

Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides

AS Kooner, H Yu, X Chen - Frontiers in immunology, 2019 - frontiersin.org
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides
that are commonly presented on the termini of glycans in higher animals and some …

Recent advances in the synthesis of 2-deoxy-glycosides

D Hou, TL Lowary - Carbohydrate research, 2009 - Elsevier
Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is
replaced with a hydrogen atom, occur widely in natural products and therefore have been …