Interest in adoptive cell therapy for treating cancer is exploding owing to early clinical
successes of autologous chimeric antigen receptor (CAR) T lymphocyte therapy. However …

Simple Summary Innate immune natural killer (NK) cells are capable of killing metastatic
cancer cells without activation by antigen-presenting cells beforehand. The cytotoxic effects …

Purpose: Adoptive transfer of tumor-infiltrating lymphocytes (TIL) can mediate regression of
metastatic melanoma. However, many patients with cancer are ineligible for such treatment …

Infusions of natural killer (NK) cells are an emerging tool for cancer immunotherapy. The
development of clinically applicable methods to produce large numbers of fully functional …

Despite advances in the diagnostic and therapeutic modalities, the prognosis of several
solid tumor malignancies remains poor. Different factors associated with solid tumors …

Natural killer (NK) cells possess potent perforin‐and interferon‐γ‐dependent effector
functions that are tightly regulated. Inhibitory receptors for major histocompatibility complex …

With the development of technologies that can transform immune cells into therapeutic
modalities, immunotherapy has remarkably changed the current paradigm of cancer …

NK cells use a variety of receptors to detect abnormal cells, including tumors and their
metastases. However, in the case of melanoma, it remains to be determined what specific …

On the basis of recent clinical and experimental data, natural killer (NK) cells appear to play
a crucial role in eradication of acute myeloid leukemias. In the present study, by exploiting …

Background aims Cancer immunotherapy involving natural killer (NK) cell infusions and
administration of therapeutic agents modulating the susceptibility of tumors to NK-cell lysis …