Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …
Small molecule modulators of alpha-synuclein aggregation and toxicity: Pioneering an emerging arsenal against Parkinson's disease
IA Ahanger, TA Dar - Ageing Research Reviews, 2024 - Elsevier
Parkinson's disease (PD) is primarily characterized by loss of dopaminergic neurons in the
substantia nigra pars compacta region of the brain and accumulation of aggregated forms of …
substantia nigra pars compacta region of the brain and accumulation of aggregated forms of …
Computational studies applied to flavonoids against Alzheimer's and Parkinson's diseases
AFM Monteiro, JDO Viana, A Nayarisseri… - Oxidative medicine …, 2018 - Wiley Online Library
Neurodegenerative diseases, such as Parkinson's and Alzheimer's, are understood as
occurring through genetic, cellular, and multifactor pathophysiological mechanisms. Several …
occurring through genetic, cellular, and multifactor pathophysiological mechanisms. Several …
Probing the molecular mechanisms of α-synuclein inhibitors unveils promising natural candidates through machine-learning QSAR, pharmacophore modeling, and …
Y Boulaamane, K Jangid, MR Britel, A Maurady - Molecular Diversity, 2024 - Springer
Parkinson's disease is characterized by a multifactorial nature that is linked to different
pathways. Among them, the abnormal deposition and accumulation of α-synuclein fibrils is …
pathways. Among them, the abnormal deposition and accumulation of α-synuclein fibrils is …
Systematic analysis of the molecular mechanisms mediated by coffee in Parkinson's disease based on network pharmacology approach
F Li, T Hatano, N Hattori - Journal of Functional Foods, 2021 - Elsevier
Many epidemiological studies have associated coffee consumption with a reduced
Parkinson's disease (PD) risk, but the molecular mechanisms remain unclear. In this study …
Parkinson's disease (PD) risk, but the molecular mechanisms remain unclear. In this study …
Prediction of parkinson's disease using machine learning techniques on speech dataset
BK Varghese, D Amali, KS Devi - Research Journal of Pharmacy …, 2019 - indianjournals.com
In the present decade of accelerated advances in Medical Sciences, most studies fail to lay
focus on ageing diseases. These are diseases that display their symptoms at a much …
focus on ageing diseases. These are diseases that display their symptoms at a much …
In Silico Study of Thymohydroquinone Interaction with blood–brain Barrier Disrupting Proteins
Aim: To evaluate the inhibitory interaction of thymohydroquinone against blood–brain barrier
(BBB)-associated neuropsychiatric and neurodegenerative disorders. Materials & methods …
(BBB)-associated neuropsychiatric and neurodegenerative disorders. Materials & methods …
[HTML][HTML] A Network Pharmacology Identified Metastasis Target for Oral Squamous Cell Carcinoma Originating from Breast Cancer with a Potential Inhibitor from F …
This study aimed to identify specific therapeutic targets for oral squamous cell carcinoma
(OSCC) that metastasize from breast cancer (BC) by using network pharmacology. The …
(OSCC) that metastasize from breast cancer (BC) by using network pharmacology. The …
Design, in-silico ADME Study and molecular docking study of novel quinoline-4-on derivatives as Factor Xa Inhibitor as Potential anti-coagulating agents
N Patadiya, V Vaghela - Asian Journal of Pharmaceutical …, 2022 - indianjournals.com
The main aim of present work is to identification of potency of novel quinoline-4-one
derivatives as a factor Xa inhibitors by in-silico ADME study and molecular docking study …
derivatives as a factor Xa inhibitors by in-silico ADME study and molecular docking study …
Recent Plant Based Remedies for Alzheimer's Disease, Parkinson's Disease and Cerebral Ischemic Stroke
P Thomas, S Jeyarani, T Choephel… - Research Journal of …, 2019 - indianjournals.com
Neurological disorders such as Alzheimer's Disease (AD), Parkinsons's Disease (PD) and
Cerebral Ischemic Stroke (CIS) are responsible for morbidities in almost a billion people and …
Cerebral Ischemic Stroke (CIS) are responsible for morbidities in almost a billion people and …