Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …

The growth plate (GP) is a cartilaginous region situated between the epiphysis and
metaphysis at the end of the immature long bone, which is susceptible to mechanical …

Bone defect repairs are based on bone graft fusion or replacement. Current large bone
defect treatments are inadequate and lack of reliable technology. Therefore, we aimed to …

The custom-tailored medicine requires a developmental strategy that integrates excellent
osteogenesis with mechanical stability to enhance the reconstruction of the critical-size bone …

Growth plates, or physis, are highly specialized cartilage tissues responsible for longitudinal
bone growth in children and adolescents. Chondrocytes that reside in growth plates are …

Growth modulation is an emerging method for treatment of angular skeletal deformities such
as adolescent idiopathic scoliosis (AIS). The Hueter‐Volkmann law, by which growth is …

MULIBREY nanism which results from autosomal recessive mutations in TRIM37 impacts
skeletal development, leading to growth delay with complications in multiple organs. In this …

Simple Summary Tibial dyschondroplasia (TD) is an avian metabolic disease characterized
by rapid apoptosis and reduced angiogenesis with compromised chondrocyte activity at the …

Macro‐scale changes in longitudinal bone growth resulting from mechanical loading were
shown in Part 1 of this review to depend on load magnitude, anatomical location, and …

The anisotropic microstructure of bone, composed of collagen fibers and biological apatite
crystallites, is an important determinant of its mechanical properties. Recent studies have …