Vertically transferred immunity in neonates: mothers, mechanisms and mediators

M Albrecht, PC Arck - Frontiers in Immunology, 2020 - frontiersin.org
Over the last years, an increasing number of outbreaks of vaccine-preventable infectious
diseases has been reported. Besides elderly and immunocompromised individuals …

Prenatal immune and endocrine modulators of offspring's brain development and cognitive functions later in life

S Schepanski, C Buss, IL Hanganu-Opatz… - Frontiers in …, 2018 - frontiersin.org
Milestones of brain development in mammals are completed before birth, which provide the
prerequisite for cognitive and intellectual performances of the offspring. Prenatal challenges …

H1N1 influenza virus infection results in adverse pregnancy outcomes by disrupting tissue-specific hormonal regulation

EQ Littauer, ES Esser, OQ Antao, EV Vassilieva… - PLoS …, 2017 - journals.plos.org
Increased susceptibility to influenza virus infection during pregnancy has been attributed to
immunological changes occurring before and during gestation in order to “tolerate” the …

Effects of vertical transmission of respiratory viruses to the offspring

S Manti, S Leonardi, F Rezaee, TJ Harford… - Frontiers in …, 2022 - frontiersin.org
Overt and subclinical maternal infections in pregnancy can have multiple and significant
pathological consequences for the developing fetus, leading to acute perinatal …

Influenza pathogenesis: the effect of host factors on severity of disease

AP Gounder, A Boon - The journal of immunology, 2019 - journals.aai.org
Influenza viruses continue to be a major global health threat. Severity and clinical outcome
of influenza disease is determined by both viral and host factors. Viral factors have long …

Obesity-related microenvironment promotes emergence of virulent influenza virus strains

R Honce, EA Karlsson, N Wohlgemuth, LD Estrada… - MBio, 2020 - Am Soc Microbiol
Obesity is associated with increased disease severity, elevated viral titers in exhaled breath,
and significantly prolonged viral shed during influenza A virus infection. Due to the mutable …

Role of inflammation in virus pathogenesis during pregnancy

A Chudnovets, J Liu, H Narasimhan, Y Liu… - Journal of …, 2020 - Am Soc Microbiol
Viral infections during pregnancy lead to a spectrum of maternal and fetal outcomes, ranging
from asymptomatic disease to more critical conditions presenting with severe maternal …

Pathogenesis of viral infections during pregnancy

PS Creisher, SL Klein - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
Viral infections during pregnancy are associated with significant adverse perinatal and fetal
outcomes. Pregnancy is a unique immunologic and physiologic state, which can influence …

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

H Jacobsen, K Walendy-Gnirß… - Nature …, 2021 - nature.com
Influenza during pregnancy can affect the health of offspring in later life, among which
neurocognitive disorders are among the best described. Here, we investigate whether …

A measles virus-based vaccine candidate mediates protection against Zika virus in an allogeneic mouse pregnancy model

C Nürnberger, BS Bodmer, AH Fiedler… - Journal of …, 2019 - Am Soc Microbiol
The impact of the Zika virus (ZIKV) epidemic highlights the need for vaccines that reduce or
prevent infection and reliably prevent teratogenic complications. The live-attenuated …