Opportunities and challenges of macrogenetic studies
The rapidly emerging field of macrogenetics focuses on analysing publicly accessible
genetic datasets from thousands of species to explore large-scale patterns and predictors of …
genetic datasets from thousands of species to explore large-scale patterns and predictors of …
Genomic insights into the conservation of wild and domestic animal diversity: a review
K Ghildiyal, SS Nayak, D Rajawat, A Sharma… - Gene, 2023 - Elsevier
Due to environmental change and anthropogenic activities, global biodiversity has suffered
an unprecedented loss, and the world is now heading toward the sixth mass extinction …
an unprecedented loss, and the world is now heading toward the sixth mass extinction …
The presence and impact of reference bias on population genomic studies of prehistoric human populations
T Günther, C Nettelblad - PLoS genetics, 2019 - journals.plos.org
Haploid high quality reference genomes are an important resource in genomic research
projects. A consequence is that DNA fragments carrying the reference allele will be more …
projects. A consequence is that DNA fragments carrying the reference allele will be more …
Wild GWAS—association mapping in natural populations
AW Santure, D Garant - Molecular ecology resources, 2018 - Wiley Online Library
The increasing affordability of sequencing and genotyping technologies has transformed the
field of molecular ecology in recent decades. By correlating marker variants with trait …
field of molecular ecology in recent decades. By correlating marker variants with trait …
Reference genomes from distantly related species can be used for discovery of single nucleotide polymorphisms to inform conservation management
Threatened species recovery programmes benefit from incorporating genomic data into
conservation management strategies to enhance species recovery. However, a lack of …
conservation management strategies to enhance species recovery. However, a lack of …
Genomic reaction norms inform predictions of plastic and adaptive responses to climate change
RA Oomen, JA Hutchings - Journal of Animal Ecology, 2022 - Wiley Online Library
Genomic reaction norms represent the range of gene expression phenotypes (usually
mRNA transcript levels) expressed by a genotype along an environmental gradient …
mRNA transcript levels) expressed by a genotype along an environmental gradient …
Batch effects in population genomic studies with low‐coverage whole genome sequencing data: Causes, detection and mitigation
RN Lou, NO Therkildsen - Molecular Ecology Resources, 2022 - Wiley Online Library
Over the past few decades, there has been an explosion in the amount of publicly available
sequencing data. This opens new opportunities for combining data sets to achieve …
sequencing data. This opens new opportunities for combining data sets to achieve …
Footprints of local adaptation span hundreds of linked genes in the Atlantic silverside genome
The study of local adaptation in the presence of ongoing gene flow is the study of natural
selection in action, revealing the functional genetic diversity most relevant to contemporary …
selection in action, revealing the functional genetic diversity most relevant to contemporary …
Genotyping‐by‐sequencing for biogeography
Aim Genotyping‐by‐sequencing (GBS) and similar reduced‐representation sequencing
methods, such as restriction site‐associated DNA sequencing (RADseq), have been …
methods, such as restriction site‐associated DNA sequencing (RADseq), have been …
Evolution of the mutation spectrum across a mammalian phylogeny
Although evolutionary biologists have long theorized that variation in DNA repair efficacy
might explain some of the diversity of lifespan and cancer incidence across species, we …
might explain some of the diversity of lifespan and cancer incidence across species, we …