[HTML][HTML] Cigarette smoke-induced reactive oxygen species formation: a concise review

YS Seo, JM Park, JH Kim, MY Lee - Antioxidants, 2023 - mdpi.com
Smoking is recognized as a significant risk factor for numerous disorders, including
cardiovascular diseases, respiratory conditions, and various forms of cancer. While the exact …

Lipid metabolism in chronic obstructive pulmonary disease

H Chen, Z Li, L Dong, Y Wu, H Shen… - International journal of …, 2019 - Taylor & Francis
Dysregulated lipid metabolism plays crucial roles in various diseases, including diabetes
mellitus, cancer, and neurodegeneration. Recent studies suggest that alterations in major …

X-and Y-linked chromatin-modifying genes as regulators of sex-specific cancer incidence and prognosis

R Tricarico, E Nicolas, MJ Hall, EA Golemis - Clinical Cancer Research, 2020 - AACR
Biological sex profoundly conditions organismal development and physiology, imposing
wide-ranging effects on cell signaling, metabolism, and immune response. These effects …

[HTML][HTML] Tobacco carcinogen induces tryptophan metabolism and immune suppression via induction of indoleamine 2, 3-dioxygenase 1

F Liang, GZ Wang, Y Wang, YN Yang, ZS Wen… - … and Targeted Therapy, 2022 - nature.com
Abstract Indoleamine 2, 3-dioxygenase 1 (IDO1), the enzyme that catabolizes tryptophan
(Trp) metabolism to promote regulatory T cells (Tregs) and suppress CD8+ T cells, is …

Integrating multi-omics and regular analyses identifies the molecular responses of zebrafish brains to graphene oxide: perspectives in environmental criteria

J Sun, Q Zhou, X Hu - Ecotoxicology and environmental safety, 2019 - Elsevier
With the broad application of nanoparticles, nanotoxicology has attracted substantial
attention in environmental science. However, the methods for detecting few and targeted …

Dysregulated mitochondrial metabolism upon cigarette smoke exposure in various human bronchial epithelial cell models

CBM Tulen, Y Wang, D Beentjes… - Disease Models & …, 2022 - journals.biologists.com
Exposure to cigarette smoke (CS) is the primary risk factor for developing chronic obstructive
pulmonary disease. The impact of CS exposure on the molecular mechanisms involved in …

[HTML][HTML] Metabolic reprogramming by tobacco-specific nitrosamines (TSNAs) in cancer

S Sarlak, C Lalou, ND Amoedo, R Rossignol - Seminars in cell & …, 2020 - Elsevier
Metabolic reprogramming is a hallmark of cancer and the link between oncogenes
activation, tumor supressors inactivation and bioenergetics modulation is well established …

Nicotine-mediated upregulation of microRNA-141 expression determines adipokine-intervened insulin resistance

A Faheem, K Rehman, K Jabeen… - Environmental Toxicology …, 2020 - Elsevier
MicroRNAs (miRNAs) are non-coding RNAs that are associated with adipokine homeostasis
and insulin resistance. Whereas, smoking can disturb metabolic homeostasis. Present study …

Role of Smoking-Mediated molecular events in the genesis of oral cancers

S Khowal, S Wajid - Toxicology mechanisms and methods, 2019 - Taylor & Francis
Smoking is a pernicious practice prevalent worldwide. It involves breathing of burnt-tobacco
fumes/smoke which comprises of numerous chemical entities posing deleterious aftermaths …

Dysregulation of mitochondrial complexes and dynamics by chronic cigarette smoke exposure utilizing MitoQC reporter mice

Q Wang, H Unwalla, I Rahman - Mitochondrion, 2022 - Elsevier
Cigarette smoke (CS) is known to cause impaired mitophagy and mitochondrial
dysregulation in the pathogenesis of chronic obstructive pulmonary disease …