Human T cell response to dengue virus infection

Y Tian, A Grifoni, A Sette, D Weiskopf - Frontiers in immunology, 2019 - frontiersin.org
DENV is a major public health problem worldwide, thus underlining the overall significance
of the proposed Program. The four dengue virus (DENV) serotypes (1–4) cause the most …

Immune-mediated pathogenesis in dengue virus infection

A Khanam, H Gutiérrez-Barbosa, KE Lyke, JV Chua - Viruses, 2022 - mdpi.com
Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …

SARS-CoV-2-specific T cells exhibit phenotypic features of helper function, lack of terminal differentiation, and high proliferation potential

J Neidleman, X Luo, J Frouard, G Xie, G Gill… - Cell Reports …, 2020 - cell.com
Summary Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …

[HTML][HTML] Dynamic SARS-CoV-2-specific B-cell and T-cell responses following immunization with an inactivated COVID-19 vaccine

Y Chen, S Yin, X Tong, Y Tao, J Ni, J Pan, M Li… - Clinical Microbiology …, 2022 - Elsevier
Objective The dynamic adaptive immune responses elicited by the inactivated virus vaccine
CoronaVac remain elusive. Methods In a prospective cohort of 100 healthcare professionals …

[PDF][PDF] Neuro-COVID long-haulers exhibit broad dysfunction in T cell memory generation and responses to vaccination

L Visvabharathy, B Hanson, Z Orban, PH Lim… - MedRxiv, 2021 - medrxiv.org
The high prevalence of post-acute sequelae of SARS-CoV-2 infection (PASC) is a significant
health concern. In particular, virus-specific immunity in patients who suffer from chronic …

Epitope prediction and identification-adaptive T cell responses in humans

J Sidney, B Peters, A Sette - Seminars in immunology, 2020 - Elsevier
Epitopes, in the context of T cell recognition, are short peptides typically derived by antigen
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …

Rapid Induction and Maintenance of Virus-Specific CD8+ TEMRA and CD4+ TEM Cells Following Protective Vaccination Against Dengue Virus Challenge in …

N Graham, P Eisenhauer, SA Diehl, KK Pierce… - Frontiers in …, 2020 - frontiersin.org
Dengue virus (DENV) is a mosquito-borne flavivirus that causes serious human disease.
The current lack of an effective vaccine to simultaneously protect against the four serotypes …

Protective heterologous T cell immunity in COVID-19 induced by the trivalent MMR and Tdap vaccine antigens

V Mysore, X Cullere, ML Settles, X Ji, MW Kattan… - Med, 2021 - cell.com
Background T cells control viral infection, promote vaccine durability, and in coronavirus
disease 2019 (COVID-19) associate with mild disease. We investigated whether prior …

Progress and applications of mass cytometry in sketching immune landscapes

T Zhang, AR Warden, Y Li… - Clinical and Translational …, 2020 - Wiley Online Library
Recently emerged mass cytometry (cytometry by time‐of‐flight [CyTOF]) technology permits
the identification and quantification of inherently diverse cellular systems, and the …

T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species

A Grifoni, H Voic, SK Dhanda, CK Kidd… - Journal of …, 2020 - Am Soc Microbiol
Members of the flavivirus genus share a high level of sequence similarity and often circulate
in the same geographical regions. However, whether T cells induced by one viral species …