A growing class of small RNAs, known as tRNA-derived RNAs (tdRs), tRNA-derived small
RNAs or tRNA-derived fragments, have long been considered mere intermediates of tRNA …

Transfer RNAs (tRNAs) decode messenger RNA codons to peptides at the ribosome. The
nuclear genome contains many tRNA genes for each amino acid and even each anticodon …

Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory
and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease, which is characterized by
the degeneration of motor neurons in the motor cortex and the spinal cord and subsequently …

Proteostasis is essential for cellular survival and particularly important for highly specialised
post‐mitotic cells such as neurons. Transient reduction in protein synthesis by protein kinase …

Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative
diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger …

The process of uncontrolled internal scarring, called fibrosis, is now emerging as a
pathological feature shared by both peripheral and central nervous system diseases. In the …

In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the
pathophysiology of neurodegenerative disorders, with a specific focus on Parkinson's …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating heterogeneous disease with
still no convincing therapy. To identify the most strategically significant hallmarks for …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease resulting in a
gradual loss of motor neuron function. Although ophthalmic complaints are not presently …