Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …

Mesenchymal stem/stromal cells (MSCs) have an immunoregulatory capacity and have
been used in different clinical protocols requiring control of the immune response. However …

Dysfunction of mRNA or RNA-binding proteins (RBPs) causes cellular aging and age-
related degenerative diseases; however, information regarding the mechanism through …

Fluorouracil (5-Fu) is the preferred drug in colorectal cancer treatment. Although 5-Fu
treatment contributes to the increase in survival rates, long-term use of 5-Fu causes severe …

In recent decades, extracellular vesicles have been recognized as “very important
particles”(VIPs) associated with aging and age-related disease. During the 1980s …

Background. The aim of this pilot clinical study is to evaluate the efficacy of human adipose
derived mesenchymal stem cells (HAMSCs) treatment for the wound healing with patients …

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by myofibroblast
abnormal activation and extracellular matrix deposition. However, the pathogenesis of PF …

Senescence in mesenchymal stem cells (MSCs) not only hinders the application of MSCs in
regenerative medicine but is also closely correlated with biological aging and the …

Fluorouracil (5-Fu) is a basic drug that is used to treat colorectal cancer. Patients who
receive 5-Fu chemotherapy often experience side effects that affect the digestive system …

Extracellular vesicles (EVs) are released by many different cell types throughout the body
and play a role in a diverse range of biological processes. EVs circulating in blood as well …