Quantifying behavior to understand the brain

TD Pereira, JW Shaevitz, M Murthy - Nature neuroscience, 2020 - nature.com
Over the past years, numerous methods have emerged to automate the quantification of
animal behavior at a resolution not previously imaginable. This has opened up a new field of …

A primer on motion capture with deep learning: principles, pitfalls, and perspectives

A Mathis, S Schneider, J Lauer, MW Mathis - Neuron, 2020 - cell.com
Extracting behavioral measurements non-invasively from video is stymied by the fact that it is
a hard computational problem. Recent advances in deep learning have tremendously …

A paradigm shift in translational psychiatry through rodent neuroethology

Y Shemesh, A Chen - Molecular psychiatry, 2023 - nature.com
Mental disorders are a significant cause of disability worldwide. They profoundly affect
individuals' well-being and impose a substantial financial burden on societies and …

Simple Behavioral Analysis (SimBA)–an open source toolkit for computer classification of complex social behaviors in experimental animals

SRO Nilsson, NL Goodwin, JJ Choong, S Hwang… - BioRxiv, 2020 - biorxiv.org
Aberrant social behavior is a core feature of many neuropsychiatric disorders, yet the study
of complex social behavior in freely moving rodents is relatively infrequently incorporated …

Deep learning-based behavioral analysis reaches human accuracy and is capable of outperforming commercial solutions

O Sturman, L von Ziegler, C Schläppi, F Akyol… - …, 2020 - nature.com
To study brain function, preclinical research heavily relies on animal monitoring and the
subsequent analyses of behavior. Commercial platforms have enabled semi high …

DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels

JP Bohnslav, NK Wimalasena, KJ Clausing, YY Dai… - Elife, 2021 - elifesciences.org
Videos of animal behavior are used to quantify researcher-defined behaviors of interest to
study neural function, gene mutations, and pharmacological therapies. Behaviors of interest …

SMART-BARN: Scalable multimodal arena for real-time tracking behavior of animals in large numbers

M Nagy, H Naik, F Kano, NV Carlson, JC Koblitz… - Science …, 2023 - science.org
The SMART-BARN (scalable multimodal arena for real-time tracking behavior of animals in
large numbers) achieves fast, robust acquisition of movement, behavior, communication …

AmadeusGPT: a natural language interface for interactive animal behavioral analysis

S Ye, J Lauer, M Zhou, A Mathis… - Advances in neural …, 2024 - proceedings.neurips.cc
The process of quantifying and analyzing animal behavior involves translating the naturally
occurring descriptive language of their actions into machine-readable code. Yet, codifying …

Three-dimensional surface motion capture of multiple freely moving pigs using MAMMAL

L An, J Ren, T Yu, T Hai, Y Jia, Y Liu - Nature Communications, 2023 - nature.com
Understandings of the three-dimensional social behaviors of freely moving large-size
mammals are valuable for both agriculture and life science, yet challenging due to …

Big behavior: challenges and opportunities in a new era of deep behavior profiling

L von Ziegler, O Sturman, J Bohacek - Neuropsychopharmacology, 2021 - nature.com
The assessment of rodent behavior forms a cornerstone of preclinical assessment in
neuroscience research. Nonetheless, the true and almost limitless potential of behavioral …