Advances in the treatment and management of frontotemporal dementia

A Benussi, B Borroni - Expert Review of Neurotherapeutics, 2023 - Taylor & Francis
Introduction Frontotemporal dementia (FTD) is a complex neurodegenerative disorder,
characterized by a wide range of pathological conditions associated with the buildup of …

Influence of periaqueductal gray on other salience network nodes predicts social sensitivity

MG Rijpma, WFZ Yang, G Toller… - Human brain …, 2022 - Wiley Online Library
The intrinsic connectivity of the salience network (SN) plays an important role in social
behavior, however the directional influence that individual nodes have on each other has …

Longitudinal assessment of social cognition in de novo Parkinson's disease patients and its relationship with dopaminergic innervation

C Trompeta, C Gasca-Salas, JA Pineda-Pardo… - Behavioural Brain …, 2023 - Elsevier
Abstract Background Social Cognition (SC) has been scarcely studied in Parkinson's
disease (PD), and findings in early disease are controversial. SC encompasses different …

Longitudinal cognitive changes in genetic frontotemporal dementia within the GENFI cohort

JM Poos, A MacDougall, E Van Den Berg, LC Jiskoot… - Neurology, 2022 - AAN Enterprises
Background and Objectives Disease-modifying therapeutic trials for genetic frontotemporal
dementia (FTD) are underway, but sensitive cognitive outcome measures are lacking. The …

How can we define the presymptomatic C9orf72 disease in 2022? An overview on the current definitions of preclinical and prodromal phases

D Saracino, I Le Ber - Revue Neurologique, 2022 - Elsevier
Repeat expansions in C9orf72 gene are the main genetic cause of frontotemporal dementia,
amyotrophic lateral sclerosis and related phenotypes. With the advent of disease-modifying …

The assessment of the socioemotional disorder in neurodegenerative diseases with the Revised Self-Monitoring Scale (RSMS)

T Dimitriou, T Parthimos, V Kamtsadeli… - Journal of Clinical …, 2022 - mdpi.com
Background: Social cognition helps people to understand their own and others' behavior
and to modulate the way of thinking and acting in different social situations. Rapid and …

Social Cognition and Mild Cognitive Impairment in Mid-Stage Parkinson's Disease

R Fernández-Fernández, G Lahera… - Behavioral …, 2024 - mdpi.com
Mild cognitive impairment (MCI) is a relevant non-motor feature in Parkinson's disease (PD).
Social cognition (SC) is a cognitive domain that refers to the ability to decode others' …

Inappropriate trusting behaviour in dementia

A Chokesuwattanaskul, D Penn, C Albero… - Frontiers in …, 2024 - frontiersin.org
Background Inappropriate trusting behaviour may have significant social, financial and other
consequences for people living with dementia. However, its clinical associations and …

Impairments in knowledge of social norms in presymptomatic, prodromal, and symptomatic frontotemporal dementia

L de Boer, E van den Berg, JM Poos… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We aimed to assess the knowledge of social norms in patients with
behavioral variant frontotemporal dementia (bvFTD) with the Dutch version of the Social …

[PDF][PDF] Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers of C9orf72

R Bruffaerts, D Gors, A Bárcenas Gallardo… - Brain …, 2022 - academic.oup.com
Traditional methods for detecting asymptomatic brain changes in neurodegenerative
diseases such as Alzheimer's disease or frontotemporal degeneration typically evaluate …