The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development
Complement-mediated synapse elimination has emerged as an important process in both
brain development and neurological diseases, but whether neurons express complement …
brain development and neurological diseases, but whether neurons express complement …
Proteoglycans and glycosaminoglycans in central nervous system injury
N Siddiqui, K Oshima… - American Journal of …, 2022 - journals.physiology.org
The brain and spinal cord constitute the central nervous system (CNS), which when injured,
can be exceedingly devastating. The mechanistic roles of proteoglycans (PGs) and their …
can be exceedingly devastating. The mechanistic roles of proteoglycans (PGs) and their …
Genotype and Injury Effect on the Expression of a Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 (SRPX2)
M Anwer, T Bolkvadze, N Puhakka, XE Ndode-Ekane… - Neuroscience, 2019 - Elsevier
Sushi repeat-containing protein X-linked 2 (SRPX2) is a novel hypothalamic protein and a
ligand of the urokinase-type plasminogen activator receptor (uPAR), which is essential for …
ligand of the urokinase-type plasminogen activator receptor (uPAR), which is essential for …
Acute Downregulation of Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 after Experimental Traumatic Brain Injury
M Anwer, L Lara-Valderrabano, J Karttunen… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) causes damage to the hypothalamo-hypophyseal axis, leading
to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to …
to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to …
Defenders of the Synapse: SRPX2 Regulates Complement Mediated Synapse Elimination in the Central Nervous System
BM Soteros - 2020 - search.proquest.com
The proper development of neural circuitry requires a delicate balance between synapse
formation and synapse elimination. While synapse formation is necessary for the initial …
formation and synapse elimination. While synapse formation is necessary for the initial …
Acute downregulation of novel hypothalamic protein sushi repeat-containing protein X-Linked 2 (SRPX2) after experimental traumatic brain injury
M Anwer, L Lara-Valderrabano, J Karttunen… - 2019 - erepo.uef.fi
Traumatic brain injury (TBI) causes damage to the hypothalamo-hypophyseal axis, leading
to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to …
to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to …