The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin

M Hoenigl, R Sprute, M Egger, A Arastehfar… - Drugs, 2021 - Springer
The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

Molecular epidemiology, antifungal susceptibility, and ERG11 gene mutation of Candida species isolated from vulvovaginal candidiasis: Comparison between …

A Esfahani, AN Omran, Z Salehi… - Microbial …, 2022 - Elsevier
Vulvovaginal candidiasis (VVC) is a prevalent infection of the genitourinary tract affecting
millions of women worldwide. In the present study, the importance of virulence factors …

Development of probiotic loaded multilayer microcapsules incorporated into dissolving microneedles for potential improvement treatment of vulvovaginal candidiasis …

CK Enggi, S Sulistiawati, S Stephanie… - Journal of Colloid and …, 2023 - Elsevier
Vulvovaginal candidiasis (VVC) is a vaginal infection caused by abnormal growth of
Candida sp., especially Candida albicans, in the vaginal mucosa. A shift in vaginal …

Biofilm Formation and Aspartyl Proteinase Activity and Their Association with Azole Resistance Among Candida albicans Causing Vulvovaginal Candidiasis, Egypt

MA Gerges, YA Fahmy, T Hosny… - Infection and Drug …, 2023 - Taylor & Francis
Background Candida albicans (C. albicans) is a major cause of vulvovaginal candidiasis
(VVC), a condition that is commonly treated with azole agents. Biofilm formation and aspartyl …

Importance of Candida infection and fluconazole resistance in women with vaginal discharge syndrome in Namibia

CM Dunaiski, MM Kock, H Jung, RPH Peters - Antimicrobial Resistance & …, 2022 - Springer
Background Vaginal discharge syndrome (VDS) is a common condition. Clinical
management targets sexually transmitted infections (STIs) and bacterial vaginosis (BV); …

Molecular epidemiology and antimicrobial resistance of vaginal Candida glabrata isolates in Namibia

CM Dunaiski, MM Kock, WY Chan, A Ismail… - Medical …, 2024 - academic.oup.com
Candida glabrata is the most common non-albicans Candida species that causes
vulvovaginal candidiasis (VVC). Given the intrinsically low susceptibility of C. glabrata to …

Combination of Farnesol with Common Antifungal Drugs: Inhibitory Effect against Candida Species Isolated from Women with RVVC

F Nikoomanesh, M Falahatinejad, L Černáková… - Medicina, 2023 - mdpi.com
Background and Objectives: Vulvovaginal candidiasis (VVC) is a mucous membrane
infection, with an increased rate of antifungal resistance of Candida species. In this study …

The antibiofilm role of biotics Family in vaginal fungal infections

A Boahen, LTL Than, YL Loke, SY Chew - Frontiers in Microbiology, 2022 - frontiersin.org
“Unity in strength” is a notion that can be exploited to characterize biofilms as they bestow
microbes with protection to live freely, escalate their virulence, confer high resistance to …

Distinct host immune responses in recurrent vulvovaginal candidiasis and vulvovaginal candidiasis

G Ge, Z Yang, D Li, N Zhang, B Chen… - Frontiers in Immunology, 2022 - frontiersin.org
Recurrent vulvovaginal candidiasis (RVVC) and vulvovaginal candidiasis (RVVC) are one of
the most common gynecological infections, primarily caused by Candida species. Although …

Antifungal effect of hydroethanolic extract of Fridericia chica (Bonpl.) LG Lohmann leaves and its therapeutic use in a vulvovaginal candidosis model

WG Lima, MGF Araújo, JCM Brito, RO Castilho… - Journal of Medical …, 2022 - Elsevier
Vulvovaginal candidosis (VVC) is one of the most frequent causes of gynecological
consultations. Therefore, the development of new antifungal therapies against VVC is …