Impact of the host microbiota on fungal infections: New possibilities for intervention?

EWL Chow, LM Pang, Y Wang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Many human fungal pathogens are opportunistic. They are primarily benign residents of the
human body and only become infectious when the host's immunity and microbiome are …

Physiological adventures in Candida albicans: farnesol and ubiquinones

KW Nickerson, DJ Gutzmann, CHT Boone… - Microbiology and …, 2024 - Am Soc Microbiol
Farnesol was first identified as a quorum-sensing molecule, which blocked the yeast to
hyphal transition in Candida albicans, 22 years ago. However, its interactions with Candida …

Impaired biosynthesis of ergosterol confers resistance to complex sphingolipid biosynthesis inhibitor aureobasidin A in a PDR16-dependent manner

S Fukuda, Y Kono, Y Ishibashi, M Tabuchi, M Tani - Scientific reports, 2023 - nature.com
Complex sphingolipids and sterols are coordinately involved in various cellular functions, eg
the formation of lipid microdomains. Here we found that budding yeast exhibits resistance to …

Azole resistance in Candida auris: mechanisms and combinatorial therapy

P Jangir, S Kalra, S Tanwar, VK Bari - APMIS, 2023 - Wiley Online Library
Multidrug resistance Candida auris is a dangerous fungal pathogen that is emerging at an
alarming rate and posing serious threats to public health. C. auris is associated with …

The pathways and the mechanisms by which Cryptococcus enters the brain

Y Zhou, Y Huang, C Yang, X Zang, H Deng, J Liu… - Mycology, 2024 - Taylor & Francis
Generally, Cryptococcus initially infects the respiratory tract, but can spread, eventually
crossing the blood-brain barrier (BBB) and causing meningitis or meningoencephalitis …

Exploring the Potential of Farnesol as a Novel Antifungal Drug and Related Challenges

D Zheng, L Yang, Y Bai, J Yong, Y Li - Current Infectious Disease Reports, 2024 - Springer
Abstract Purpose of Review Farnesol (FOH) is a quorum-sensing molecule with potential as
an antifungal drug. Given the growing concern about fungal drug resistance, exploring new …

Effectiveness of Farnesol for treatment of dog otitis complicated by Malassezia pachydermatis

IR Olabode, NP Sachivkina… - RUDN Journal of …, 2023 - agrojournal.rudn.ru
The study involved 30 dogs with otitis complicated by Malassezia pachydermatis. The
animals were divided into 2 groups: experimental (n= 15) and control (n= 15). The …

МОРФОЛОГИЧЕСКИЕ ПОКАЗАТЕЛИ КРОВИ СОБАК ПРИ ЛЕЧЕНИИ МАЛАЦЕЗИОЗНОГО ОТИТА С ИСПОЛЬЗОВАНИЕМ ФАРНЕЗОЛА

ВВ Виссарионова, ИР Олабодэ, ЮА Ватников… - ББК 72я43 Н60, 2023 - elibrary.ru
В настоящее время наблюдается тенденция к увеличению заболеваемости
оппортунистическими микозами не только людей, но и животных. На смену …