MicroRNA-122 in human cancers: from mechanistic to clinical perspectives

M Faramin Lashkarian, N Hashemipour… - Cancer Cell …, 2023 - Springer
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that can regulate the
expression of target genes post-transcriptionally and interact with mRNA-coding genes …

Clinical significance of microRNAs in hematologic malignancies and hematopoietic stem cell transplantation

A Sevcikova, I Fridrichova, N Nikolaieva, L Kalinkova… - Cancers, 2023 - mdpi.com
Simple Summary Dysregulated microRNA (miRNA) expression has been described in the
initiation and progression of a wide spectrum of hematologic malignancies. Moreover …

Implication of microRNAs in carcinogenesis with emphasis on hematological malignancies and clinical translation

Z Gaál - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …

Empowering Graph Neural Networks with Block-Based Dual Adaptive Deep Adjustment for Drug Resistance-Related NcRNA Discovery

Y Zhang, X Li - Journal of Chemical Information and Modeling, 2024 - ACS Publications
Drug resistance to chemotherapeutic agents remains a formidable challenge in cancer
treatment, significantly impacting treatment efficacy. Extensive research has exposed the …

Epigenetic modification of miRNA in cancer

C Sona, S Aneta, F Ivana - Personalized Epigenetics, 2024 - Elsevier
MicroRNAs (miRNAs) are single-stranded noncoding RNA molecules affecting key cellular
processes under normal physiological conditions. miRNA biogenesis involves multiple …

BCR: ABL1-induced leukemogenesis: impacts of miR-495 and circadian clock

Y Rittavee - 2022 - theses.hal.science
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the
presence of an abnormal chimeric fusion protein BCR:: ABL1. The treatment of CML has …