Complex diseases (eg, Alzheimer's disease) or infectious diseases are usually caused by
complicated and varied factors, including environmental and genetic factors. Multi-target …

Bone marrow Mesenchymal Stem Cells (BM-MSCs), due to their strong protective and anti-
inflammatory abilities, have been widely investigated in the context of several diseases for …

Introduction Most methods in molecular and drug design are currently based on
physicochemical descriptors. However, molecular topology, which relies on topological …

Background Mounting evidences indicate that oxidative stress, neuroinflammation, and
dysregulation of gut microbiota are related to neurodegenerative disorders (NDs) …

Neurodegenerative diseases (NDs) like Alzheimer's disease, multiple sclerosis, amyotrophic
lateral sclerosis, Parkinson's disease, and Huntington's disease predominantly pose a …

Objective (s): Metformin, as an insulin sensitizer, is a familiar antidiabetic drug. Increasing
evidence points to metformin's protective effects against Alzheimer's disease (AD). However …

A prototype of a family of at least nine members, cellular Src tyrosine kinase is a
therapeutically interesting target because its inhibition might be of interest not only in a …

Protein misfolding is fundamental to a number of human disorders including Alzheimer's
disease, prion diseases, Parkinson's disease and type 2 diabetes mellitus. To date, there …

阿尔茨海默病(Alzheimer's disease, AD) 是最常见的老年性神经退行性疾病之一,
严重威胁着老年人的健康. 目前被批准用于治疗AD 的药物只能缓解AD 的症状, 不能治愈AD …

Among neurodegenerative disorders, Alzheimer's disease (AD) is the most common type of
dementia, and there is an urgent need to discover new and efficacious forms of treatment for …