Periodontitis (PD) is a common chronic infectious disease. The local inflammatory response
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …

Bone is an active tissue, being constantly renewed in healthy individuals with participation of
the immune system to a large extent. Any imbalance between the processes of bone …

Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free
therapeutics involving MSCs and the contents can be customized under disease-associated …

Bioceramics have been extensively used to improve osteogenesis of polymers because of
their excellent bone-forming capabilities. However, the inadequate interfacial bonding …

Abstract Bone morphogenetic protein (BMP-2) has been approved by the FDA to promote
bone regeneration, but uncertain osteogenic effect and dose-dependent side effects may …

Bone healing is associated with many orthopedic conditions, including fractures and
osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle …

The disability rate of joint diseases can be reduced by the use of artificial joints, but joint
loosening at a late state limits the lifespan and surgical efficacy of the joints. Wear particles …

Exosomes are extracellular vesicles (EVs) containing various ingredients such as DNA,
RNA, lipids and proteins, which play a significant role in intercellular communication …

With the discovery of the intrinsic enzyme‐like activity of metal oxides, nanozymes garner
significant attention due to their superior characteristics, such as low cost, high stability, multi …

Macrophages (Mφs) are master regulators of the immune response and may serve as
therapeutic targets in aging societies. This study aimed to determine the function of M1Mφ …